Deupirfenidone

DRUG3 trials

Sponsors

PureTech

Conditions

Idiopathic Pulmonary FibrosisIdiopathic Pulmonary Fibrosis (IPF)Pharmacokinetic Analysis

Phase 1

PK of Deupirfenidone Versus Pirfenidone in Older Healthy Subjects

CompletedNCT07456800

PureTechPharmacokinetic Analysis

Start: 2021-07-12End: 2022-01-20Updated: 2026-03-06

Phase 2

LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Active, not recruitingNCT05321420

PureTechIdiopathic Pulmonary Fibrosis

Start: 2022-07-22End: 2025-12-31Target: 240Updated: 2025-10-16

Phase 3

Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)

RecruitingNCT07284602

PureTechIdiopathic Pulmonary Fibrosis (IPF)

Start: 2026-06-26End: 2029-12-01Target: 1100Updated: 2026-09-03

Related Papers

Deupirfenidone compared with pirfenidone and placebo in idiopathic pulmonary fibrosis (ELEVATE-IPF): a phase 2b randomized placebo-controlled trial.

2026-08-01