Depot medroxyprogesterone acetate (DMPA)

DRUG4 trials

Sponsors

Nationwide Children's Hospital, Lisa Haddad, Emory University, University of Pennsylvania

Conditions

ContraceptionDisorder of Bone Density and Structure, UnspecifiedHIVHormonal ContraceptionSickle Cell Disease (SCD)Uterine BleedingVaso-Occlusive Pain Episode in Sickle Cell DiseaseWeight Gain

Phase 3

Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects

CompletedNCT01461824

Nationwide Children's HospitalDisorder of Bone Density and Structure, Unspecified, Uterine Bleeding, Weight Gain

Start: 2011-09-30End: 2016-07-31Updated: 2018-04-23

Phase 4

Impact of Hormonal Contraception on HIV Acquisition and Transmission Risk

CompletedNCT02357368

Lisa HaddadContraception, HIV

Start: 2015-02-28End: 2019-10-23Updated: 2020-11-18

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

RecruitingNCT06665997

University of PennsylvaniaSickle Cell Disease (SCD), Vaso-Occlusive Pain Episode in Sickle Cell Disease

Start: 2025-06-26End: 2028-07-31Target: 65Updated: 2026-05-28

Unknown Phase

Contraceptive Hormones, Immunity, and Microbiome Evaluation

CompletedNCT03660046

Emory UniversityHormonal Contraception

Start: 2018-12-07End: 2023-09-07Updated: 2024-10-29