Dendritic Cells Vaccine

BIOLOGICAL4 trials

Sponsors

Clinica Universidad de Navarra, Universidad de Navarra, Macarena De La Fuente, MD, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Conditions

Bone SarcomaColorectal CarcinomaGlioblastomaHepatic MetastasisSarcomaSoft Tissue Sarcoma

Phase 1

Dendritic Cell Vaccine for Children and Adults With Sarcoma

CompletedNCT01803152

Macarena De La Fuente, MDBone Sarcoma, Sarcoma, Soft Tissue Sarcoma

Start: 2014-01-06End: 2024-06-21Updated: 2024-07-03

Immunotherapy With Autologous Tumor Lysate-Loaded Dendritic Cells In Patients With Recurrence Of Glioblastoma Multiforme

TerminatedNCT04002804

Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaGlioblastoma

Start: 2010-04-30End: 2017-06-13Updated: 2019-07-01

Immunotherapy With Autologous Tumor Lysate-Loaded Dendritic Cells In Patients With Newly Diagnosed Glioblastoma Multiforme

CompletedNCT04801147

Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaGlioblastoma

Start: 2010-06-26End: 2024-12-31Target: 76Updated: 2026-03-27

Phase 2

Study With Dendritic Cell Immunotherapy in Resected Hepatic Metastasis of Colorectal Carcinoma

Clinica Universidad de Navarra, Universidad de NavarraColorectal Carcinoma, Hepatic Metastasis

Start: 2010-11-30End: 2018-12-31Target: 58Updated: 2017-10-24

Related Papers

Immune landscape of sarcoma patients treated with an autologous dendritic cell vaccine.

Journal of Clinical Oncology2025-05-28

JS07.5.A CORRELATION BETWEEN TUMOR-INFILTRATING LYMPHOCYTE DISTRIBUTION AND CLINICAL OUTCOME IN PHASE I/II CLINICAL TRIAL OF DENDRITIC-CELL BASED IMMUNOTHERAPY IN GLIOBLASTOMA PATIENTS

Neuro-Oncology2024-10-01

Abstract 4694: Single-cell analysis of glioblastoma immune contexture identifies a subset of activated and memory tumor-reactive CD8+ TILs and a Treg signature contributing to TIL irreversible dysfunction

Cancer Research2023-04-04

Phase 1 trial of autologous dendritic cell vaccination with imiquimod immunomodulation in children and adults with refractory sarcoma.

Journal of Clinical Oncology2021-05-204 citations

A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis

Journal for ImmunoTherapy of Cancer2018-09-2955 citations

Randomized phase II study with dendritic cell (DC) immunotherapy in patients with resected hepatic metastasis of colorectal carcinoma.

Journal of Clinical Oncology2014-05-201 citations