Delgocitinib cream vehicle

DRUG6 trials

Sponsors

LEO Pharma

Conditions

Atopic DermatitisChronic Hand EczemaDiscoid Lupus ErythematosusFrontal Fibrosing AlopeciaHealthy Volunteers

Phase 1

Clinical Trial to Evaluate Light-induced Skin Reactions After Application of Delgocitinib Cream

CompletedNCT04361136

LEO PharmaHealthy Volunteers

Start: 2020-04-23End: 2020-05-30Updated: 2025-02-24

Clinical Trial to Evaluate UV-light-induced Allergic Skin Reactions After Application of Delgocitinib Cream

CompletedNCT04807751

LEO PharmaHealthy Volunteers

Start: 2021-03-25End: 2021-07-30Updated: 2025-02-24

Phase 2

Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema

CompletedNCT03683719

LEO PharmaChronic Hand Eczema

Start: 2018-11-28End: 2020-04-20Updated: 2025-03-12

Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over an 8-week Treatment Period in Adult Subjects With Atopic Dermatitis.

CompletedNCT03725722

LEO PharmaAtopic Dermatitis

Start: 2018-12-28End: 2020-05-19Updated: 2025-03-12

Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.

TerminatedNCT03958955

LEO PharmaDiscoid Lupus Erythematosus

Start: 2019-07-09End: 2020-04-30Updated: 2025-03-06

A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing Alopecia

CompletedNCT05332366

LEO PharmaFrontal Fibrosing Alopecia

Start: 2022-04-19End: 2023-05-22Updated: 2025-03-06

Related Papers

Randomized Controlled Trial of the Topical Jak Inhibitor Delgocitinib Cream in Patients with Frontal Fibrosing Alopecia.

2025-10-141 citations

Health-Related Quality of Life in Chronic Hand Eczema in a Phase 2b Trial of Delgocitinib Cream

Dermatology and Therapy2025-04-05

Development and Validation of a Patient-Reported Outcome Measure of the Impact of Chronic Hand Eczema on Health-Related Quality of Life: the Hand Eczema Impact Scale (HEIS)

Dermatology and Therapy2024-10-215 citations

Validation of the Investigator Global Assessment of Chronic Hand Eczema (IGA–CHE): a new clinician reported outcome measure of CHE severity

Archives of Dermatological Research2024-03-2016 citations

Development and Psychometric Validation of a Patient-Reported Outcome Measure to Assess the Signs and Symptoms of Chronic Hand Eczema: The Hand Eczema Symptom Diary (HESD).

2024-03-157 citations

Treatment with delgocitinib cream improves itch, pain and other signs and symptoms of chronic hand eczema: Results from the Hand Eczema Symptom Diary in a phase <scp>IIb</scp> randomized clinical trial

Contact Dermatitis2023-04-1024 citations