deglycosylated ricin A chain-conjugated anti-CD19/anti-CD22 immunotoxins

BIOLOGICAL2 trials

Sponsors

Albert Einstein College of Medicine

Conditions

Adult B Acute Lymphoblastic LeukemiaLeukemiaRecurrent Adult Acute Lymphoblastic Leukemia

Phase 1

Anti-CD19 and Anti-CD22 Immunotoxins in Treating Patients With Refractory or Relapsed B-Cell Acute Lymphoblastic Leukemia

CompletedNCT00450944

Albert Einstein College of MedicineLeukemia

Start: 2006-02-22End: 2010-04-01Updated: 2021-04-14

Immunotoxin Therapy and Cytarabine in Treating Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia

TerminatedNCT01408160

Albert Einstein College of MedicineAdult B Acute Lymphoblastic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia

Start: 2013-04-30End: 2018-06-26Updated: 2019-09-06

Related Papers

Synergy of sequential administration of a deglycosylated ricin A chain-containing combined anti-CD19 and anti-CD22 immunotoxin (Combotox) and cytarabine in a murine model of advanced acute lymphoblastic leukemia.

2012-04-1820 citations