Deflazacort
Sponsors
Pfizer Inc., Ludwig-Maximilians - University of Munich, University of Rochester, PTC Therapeutics, Post Graduate Institute of Medical Education and Research, Chandigarh
Conditions
Active Idiopathic Inflammatory Myopathies (Including Dermatomyositis or Polymyositis)Allergic Bronchopulmonary AspergillosisDuchenne Muscular DystrophyDysferlinopathyHealthy VolunteersHepatic ImpairmentIdiopathic Inflammatory Myopathy (including dermatomyositis or polymyositis)LGMD2B
Phase 1
A Pharmacokinetic Study of Oral Deflazacort in Children and Adolescent Subjects With Duchenne Muscular Dystrophy
CompletedNCT02251600
Start: 2014-12-31End: 2015-10-31Updated: 2017-08-18
A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics
CompletedNCT02286609
Start: 2014-12-31End: 2015-02-28Updated: 2017-08-18
A Single Dose Evaluation of the Effects of Renal Impairment on Deflazacort Pharmacokinetics
CompletedNCT02286622
Start: 2014-12-31End: 2015-02-28Updated: 2017-08-18
An Open-Label, Long-Term Extension Study to Evaluate the Safety and Tolerability Deflazacort
CompletedNCT02295748
Start: 2014-12-31End: 2017-08-24Updated: 2017-12-08
Food Effect and Bioavailability of Deflazacort Formulations in Healthy Volunteers
CompletedNCT02485431
Start: 2015-06-30End: 2015-08-31Updated: 2017-08-18
Study of the Excretion of Orally Administered Corticosteroids for the Improval of the Detection of Said Substances in Anti-doping Controls
NCT04791345
Start: 2021-02-26End: 2022-02-26Target: 50Updated: 2021-04-01
Phase 2
Phase 3
Finding the Optimum Regimen for Duchenne Muscular Dystrophy
CompletedNCT01603407
Start: 2013-01-31End: 2019-11-30Updated: 2022-08-12
A Study of Deflazacort (Emflaza®) in Participants With Duchenne Muscular Dystrophy (DMD)
WithdrawnNCT03642145
Start: 2018-10-31End: 2021-07-31Updated: 2019-06-21
A Study of Deflazacort (Emflaza®) in Participants With Limb-Girdle Muscular Dystrophy 2I (LGMD2I)
TerminatedNCT03783923
Start: 2019-10-31End: 2021-01-01Updated: 2022-06-27
C0251006 - A PHASE 3, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-06823859 IN PARTICIPANTS WITH ACTIVE IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH ACTIVE DERMATOMYOSITIS OR POLYMYOSITIS)
RecruitingCTIS2022-502739-20-00
Start: 2023-11-16Target: 79Updated: 2025-12-17
C0251010 - A PHASE 3, MULTI-CENTER, OPEN-LABEL EXTENSION STUDY TO INVESTIGATE THE LONG-TERM SAFETY, TOLERABILITY, AND EFFICACY OF DAZUKIBART IN PARTICIPANTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH DERMATOMYOSITIS OR POLYMYOSITIS)
RecruitingCTIS2024-514648-10-00
Start: 2025-03-14Target: 21Updated: 2025-11-25