Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension

DRUG3 trials

Sponsors

Lantheus Medical Imaging, Sunnybrook Health Sciences Centre

Conditions

ALSAmyotrophic Lateral SclerosisBrain Tumor AdultBrain Tumor, PrimaryGBMGlioblastoma Multiforme (GBM)Glioblastoma Multiforme GliomaGlioblastoma Multiforme of Brain

Phase 1

Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy

RecruitingNCT07179328

Sunnybrook Health Sciences CentreBrain Tumor Adult, Brain Tumor, Primary, GBM +5

Start: 2025-06-04End: 2027-11-30Target: 10Updated: 2025-09-17

Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)

Active, not recruitingNCT07193953

Sunnybrook Health Sciences CentreALS, Amyotrophic Lateral Sclerosis

Start: 2025-04-15End: 2027-05-30Target: 6Updated: 2026-07-14

Phase 4

DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function

CompletedNCT00401687

Lantheus Medical ImagingVentricular Ejection Fraction

Start: 2006-07-31End: 2008-04-30Updated: 2011-05-20