de-escalated radiotherapy

RADIATION3 trials

Sponsors

The Netherlands Cancer Institute, Sun Yat-sen University, Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Conditions

HNSCCHead and Neck Squamous Cell CarcinomaIMMUNOTHERAPYLocally Advanced Head and Neck CancerNasopharyngeal CarcinomaProstate CancerRadiotherapy; Complications

Phase 2

Induction Chemoimmunotherapy Followed by Deescalated Definitive Radiotherapy in Head and Neck Cancer

Active, not recruitingNCT07791602

Cancer Institute and Hospital, Chinese Academy of Medical SciencesHead and Neck Squamous Cell Carcinoma, Locally Advanced Head and Neck Cancer, HNSCC

Start: 2026-06-12End: 2032-12-01Target: 180Updated: 2026-08-28

Unknown Phase

A Pilot Study of Dose dE-eScalaTion IN prostATe radIOtherapy usiNg the MRL

Active, not recruitingNCT06284304

The Netherlands Cancer InstituteProstate Cancer

Start: 2024-02-29End: 2027-04-02Updated: 2026-02-04

De-escalated Radiotherapy for Primary Tumor After Neoadjuvant Therapy With Toripalimab Plus Chemotherapy for Nasopharyngeal Carcinoma

RecruitingNCT06313450

Sun Yat-sen UniversityNasopharyngeal Carcinoma, Radiotherapy; Complications, IMMUNOTHERAPY

Start: 2024-03-04End: 2028-02-01Target: 112Updated: 2024-03-19