DB107-RRV

DRUG2 trials

Sponsors

Ashish Shah, University of California, San Francisco

Conditions

Anaplastic AstrocytomaHigh Grade GliomaMGMT-Methylated GlioblastomaMGMT-Unmethylated Glioblastoma

Phase 1

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

RecruitingNCT06504381

University of California, San FranciscoHigh Grade Glioma, MGMT-Methylated Glioblastoma, MGMT-Unmethylated Glioblastoma

Start: 2025-01-08End: 2042-01-31Target: 70Updated: 2026-03-11

Phase 2

DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

RecruitingNCT06264388

Ashish ShahAnaplastic Astrocytoma, High Grade Glioma

Start: 2024-05-01End: 2034-05-01Target: 33Updated: 2025-05-29