DaTscan

DRUG7 trials

Conditions

Alzheimer DiseaseAlzheimer'sAlzheimer's DiseaseHealthy VolunteersLewy Body DementiaNon-DLB DementiaParkinson DiseaseParkinson's Disease

Early Phase 1

Phase 0 Evaluation of [18F]MNI-958 as a Potential PET Radioligand for Imaging Tau Protein in the Brain

CompletedNCT03058965

Molecular NeuroImagingAlzheimer Disease, Healthy Volunteers, Progressive Supranuclear Palsy

Start: 2016-11-29End: 2018-05-11Updated: 2019-03-25

Phase 2

Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression

CompletedNCT01141023

Ken Marek, MDParkinson Disease

Start: 2010-06-30End: 2020-06-30Updated: 2023-11-14

Phase 3

Dopamine Transporter Scintigraphy Imaging (DAT-Imaging) in Patients With Lewy Body Dementia

CompletedNCT00209456

GE HealthcareAlzheimer's, Lewy Body Dementia, Non-DLB Dementia +1

Start: 2003-11-30Target: 326Updated: 2007-05-16

A Cross-Over, Multi-Center Trial to Evaluate the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes

WithdrawnNCT01950468

Navidea BiopharmaceuticalsParkinson's Syndrome

Start: 2017-04-30End: 2018-03-31Updated: 2017-09-13

Unknown Phase

Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease

RecruitingNCT03019757

Douglas ScharreAlzheimer's Disease, Lewy Body Dementia, Parkinson's Disease

Start: 2018-08-30End: 2026-12-31Target: 76Updated: 2025-03-30

Nigrosomal Iron Imaging in Parkinson's Disease

NCT03022357

University of NottinghamParkinson Disease

Start: 2016-06-30End: 2019-05-31Target: 145Updated: 2018-10-12

Markers of Disease Progression and Gait Within the Parkinsonian Population

CompletedNCT04653688

University Hospital, LilleParkinson Disease

Start: 2020-12-22End: 2024-10-17Updated: 2025-12-04

BMC Neurology2026-07-02

Temporal Dynamics and Cross-Sectional and Longitudinal Factors Associated With Motor Reserve and Outcome in Patients With Parkinson Disease.

2025-12-26

Machine learning-based stratification of mild cognitive impairment in Parkinson's disease: a multicenter cross-sectional analysis.

2025-10-151 citations

Diagnostic Value of Swallow Tail Sign at Brain MRI in Patients with Clinically Uncertain Parkinsonian Syndrome.

PubMed2025-07-012 citations

Parkinson's disease psychosis associated with accelerated multidomain cognitive decline.

2024-07-238 citations

Association of Family History and Polygenic Risk Score With Longitudinal Prognosis in Parkinson Disease

Neurology Genetics2023-12-084 citations

High-Throughput CSF Proteomics and Machine Learning to Identify Proteomic Signatures for Parkinson Disease Development and Progression.

2023-08-1623 citations

Current coffee consumption is associated with decreased striatal dopamine transporter availability in Parkinson's disease patients and healthy controls.

2023-07-256 citations

Prognostic significance of peripheral neutrophils and lymphocytes in early untreated Parkinson’s disease: an 8-year follow-up study

Journal of Neurology Neurosurgery & Psychiatry2023-07-1421 citations

Impact of the Dopamine System on Long‐Term Cognitive Impairment in Parkinson Disease: An Exploratory Study

Movement Disorders Clinical Practice2023-04-119 citations

Updated Percentiles for the University of Pennsylvania Smell Identification Test in Adults 50 Years of Age and Older

Neurology2023-02-2759 citations

Long-term Effect of Regular Physical Activity and Exercise Habits in Patients With Early Parkinson Disease.

2022-01-12137 citations

Association of Physical Activity and APOE Genotype With Longitudinal Cognitive Change in Early Parkinson Disease.

2021-03-3119 citations

Motor Progression in Early-Stage Parkinson's Disease: A Clinical Prediction Model and the Role of Cerebrospinal Fluid Biomarkers

Frontiers in Aging Neuroscience2021-01-2517 citations

Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross‐Sectional Study

Movement Disorders2020-02-1973 citations

Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): a cross-sectional study.

2019-10-31114 citations

Protocol of a single group prospective observational study on the diagnostic value of 3T susceptibility weighted MRI of nigrosome-1 in patients with parkinsonian symptoms: the N3 i PD study (nigrosomal i ron i maging i n Parkinson’s disease)

BMJ Open2017-12-018 citations

Baseline prevalence and longitudinal evolution of non-motor symptoms in early Parkinson’s disease: the PPMI cohort

Journal of Neurology Neurosurgery & Psychiatry2017-10-06113 citations

Large-scale identification of clinical and genetic predictors of motor progression in patients with newly diagnosed Parkinson's disease: a longitudinal cohort study and validation.

2017-09-25121 citations

Incident impulse control disorder symptoms and dopamine transporter imaging in Parkinson disease

Journal of Neurology Neurosurgery & Psychiatry2015-11-03126 citations

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