DAS181

DRUG10 trials

Conditions

COVID-19HealthyImmunocompromisedInfluenzaInfluenza InfectionLower Respiratory Tract InfectionParainfluenzaParainfluenza Infection

Phase 1

Single Dose Escalating Study of DAS181 in Adults

CompletedNCT00527865

Ansun Biopharma, Inc.Influenza

Start: 2007-10-31End: 2009-01-31Target: 36Updated: 2009-01-08

DAS181 Single Dose Escalation Study in Healthy Adults

CompletedNCT00876161

Ansun Biopharma, Inc.Healthy

Start: 2009-05-18End: 2010-05-23Updated: 2019-08-02

Influenza Antiviral DAS181-F03

CompletedNCT01173224

National Institute of Allergy and Infectious Diseases (NIAID)Influenza

Start: 2010-11-30End: 2011-09-30Updated: 2013-07-19

Influenza Antiviral DAS-181-F04 in Healthy Adults

CompletedNCT01651494

National Institute of Allergy and Infectious Diseases (NIAID)Influenza

Start: 2011-08-12End: 2012-09-18Updated: 2017-04-07

Phase 2

DAS181 in Patients With Parainfluenza

WithdrawnNCT01441024

National Institute of Allergy and Infectious Diseases (NIAID)Parainfluenza Infection

Start: 2011-07-14End: 2014-06-30Updated: 2019-12-17

DAS181 for Patients With Severe Hospitalized Flu and SAD-RVs (COVID-19)

NCT04298060

Ansun Biopharma, Inc.Influenza Infection, SAD-RV Infection and COVID-19

Start: 2020-07-31End: 2022-09-30Target: 280Updated: 2020-07-09

DAS181 for STOP COVID-19

WithdrawnNCT04354389

Ansun Biopharma, Inc.COVID-19

Start: 2020-07-25End: 2020-11-30Updated: 2020-08-11

Phase 3

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

RecruitingNCT03808922

Ansun Biopharma, Inc.COVID-19, Immunocompromised, Lower Respiratory Tract Infection +1

Start: 2019-05-23End: 2028-09-01Target: 274Updated: 2026-06-23

Unknown Phase

DAS181 for Severe COVID-19: Compassionate Use

CompletedNCT04324489

Renmin Hospital of Wuhan UniversityCOVID-19

Start: 2020-03-06End: 2020-04-30Updated: 2020-05-05

Worldwide Trends on COVID-19 Research After the Declaration of COVID-19 Pandemic

NCT04460547

Qassim UniversityCOVID-19

Start: 2020-07-25End: 2020-09-20Target: 200Updated: 2020-07-07

Related Papers

Smartphone-Guided Self-prone Positioning vs Usual Care in Nonintubated Hospital Ward Patients With COVID-19: A Pragmatic Randomized Clinical Trial.

2022-05-1826 citations

DAS181 Treatment of Severe Lower Respiratory Tract Parainfluenza Virus Infection in Immunocompromised Patients: A Phase 2 Randomized, Placebo-Controlled Study

Clinical Infectious Diseases2021-02-0527 citations

Resolution of Coronavirus Disease 2019 Infection and Pulmonary Pathology With Nebulized DAS181: A Pilot Study

Critical Care Explorations2020-10-014 citations