darexaban

DRUG5 trials

Sponsors

Astellas Pharma Inc

Conditions

Healthy SubjectsPharmacodynamic InteractionPharmacodynamic and Pharmacokinetic InteractionPharmacokinetics of Darexaban and Metabolites

Phase 1

To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)

CompletedNCT01405989

Astellas Pharma IncHealthy Subjects, Pharmacokinetics of Darexaban and Metabolites

Start: 2010-01-31End: 2010-03-31Updated: 2014-03-05

To Evaluate if Multiple Doses of Rifampicin Change the Blood Concentration of YM150 (Darexaban)

CompletedNCT01406002

Astellas Pharma IncHealthy Subjects, Pharmacokinetics of Darexaban and Metabolites

Start: 2010-01-31End: 2010-03-31Updated: 2013-04-11

To Evaluate Whether Acetyl Salicylic Acid (Aspirin), the Combination of Aspirin and Clopidogrel and Darexaban (YM150) Interact in Their Effects

CompletedNCT01409616

Astellas Pharma IncHealthy Subjects, Pharmacodynamic Interaction

Start: 2009-04-30End: 2009-09-30Updated: 2013-03-21

To Evaluate Whether Naproxen and Darexaban (YM150) Interact in Their Effects

CompletedNCT01409603

Astellas Pharma IncHealthy Subjects, Pharmacodynamic Interaction

Start: 2010-01-31End: 2010-05-31Updated: 2013-04-11

To Evaluate Whether Acetyl Salicylic Acid (Aspirin) and Darexaban (YM150) Interact in Their Effects

CompletedNCT01424332

Astellas Pharma IncHealthy Subjects, Pharmacodynamic and Pharmacokinetic Interaction

Start: 2007-12-31End: 2008-03-31Updated: 2011-08-29