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dapivirine

DRUG11 trials

Sponsors

International Partnership for Microbicides, Inc.

Conditions

Acquired Immunodeficiency SyndromeHIVHIV InfectionsHIV-1-infectionHealthyHuman Immunodeficiency VirusTopical Penile Exposures

Phase 1

An Expanded Safety Study of Dapivirine Gel 4759 in Africa
CompletedNCT00917891
International Partnership for Microbicides, Inc.Acquired Immunodeficiency Syndrome, HIV Infections
Start: 2009-11-30End: 2011-09-30Updated: 2011-09-12
An Expanded Safety Study of Dapivirine Gel 4789 in Africa
CompletedNCT00917904
International Partnership for Microbicides, Inc.Acquired Immunodeficiency Syndrome, Healthy, HIV Infections
Start: 2009-07-31End: 2010-09-30Updated: 2011-12-14
A Safety Study of Dapivirine Vaginal Ring in Africa
CompletedNCT01071174
International Partnership for Microbicides, Inc.HIV Infections
Start: 2010-04-30End: 2011-07-31Updated: 2011-08-02
A Safety Study to Assess the Delivery of Dapivirine From a Matrix Vaginal Ring
CompletedNCT01144676
International Partnership for Microbicides, Inc.HIV Infections
Start: 2010-04-30End: 2010-09-30Updated: 2010-10-06
Male Tolerance Study of Dapivirine Gel Following Multiple Topical Penile Exposures
CompletedNCT01277640
International Partnership for Microbicides, Inc.Topical Penile Exposures
Start: 2011-03-31End: 2011-07-31Updated: 2017-09-08
DDI Potential: Dapivirine Vaginal Ring and Miconazole Nitrate
CompletedNCT01731574
International Partnership for Microbicides, Inc.HIV
Start: 2012-12-31End: 2013-10-31Updated: 2017-09-08
Pharmacokinetic Study of the Dapivirine Vaginal Ring in Lactating Women
CompletedNCT02808949
International Partnership for Microbicides, Inc.Human Immunodeficiency Virus
Start: 2015-02-28End: 2018-03-03Target: 16Updated: 2018-03-13
Relative Bioavailability Trial of Dapivirine Ring-004 and Ring-008
CompletedNCT05416021
International Partnership for Microbicides, Inc.HIV Infections
Start: 2022-08-01End: 2024-07-02Updated: 2024-07-03

Phase 2

Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)
WithdrawnNCT03074786
International Partnership for Microbicides, Inc.HIV-1-infection
Start: 2017-11-30End: 2020-12-30Updated: 2017-09-08

Phase 3

A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa
WithdrawnNCT01337570
International Partnership for Microbicides, Inc.HIV Infections
Start: 2011-07-31End: 2014-07-31Updated: 2012-06-11
A Safety and Efficacy Trial of Dapivirine Vaginal Ring in Africa
WithdrawnNCT01337583
International Partnership for Microbicides, Inc.HIV Infections
Start: 2011-07-31End: 2014-07-31Updated: 2012-06-11

Related Papers

Correlates of Adherence to Oral and Vaginal Pre-exposure Prophylaxis (PrEP) Among Adolescent Girls and Young Women (AGYW) Participating in the MTN-034/REACH Trial.
2024-06-098 citations
Pharmacokinetics of Dapivirine Transfer into Blood Plasma, Breast Milk, and Cervicovaginal Fluid of Lactating Women Using the Dapivirine Vaginal Ring.
2019-02-2621 citations
Safety, Acceptability and Adherence of Dapivirine Vaginal Ring in a Microbicide Clinical Trial Conducted in Multiple Countries in Sub-Saharan Africa
PLoS ONE2016-03-10110 citations