Dantrolene

DRUG8 trials

Conditions

Cerebral VasospasmCerebral Vasospasm After Subarachnoid HemorrhageHealthy VolunteersHyperthermiaLumbar Spine InjuryMultiple SclerosisStatins Induced MyopathySubarachnoid Hemorrhage

Phase 1

Safety Study of Dantrolene to Treat Cerebral Vasospasm After Subarachnoid Hemorrhage

CompletedNCT00964548

University of Massachusetts, WorcesterCerebral Vasospasm After Subarachnoid Hemorrhage

Start: 2007-07-31End: 2009-10-31Updated: 2012-05-25

Safety Study of Dantrolene in Subarachnoid Hemorrhage

CompletedNCT01024972

University of Massachusetts, WorcesterCerebral Vasospasm, Subarachnoid Hemorrhage

Start: 2009-10-31End: 2013-10-31Updated: 2015-03-05

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

RecruitingNCT03109288

National Institute of Allergy and Infectious Diseases (NIAID)Multiple Sclerosis

Start: 2017-08-11End: 2029-01-01Target: 250Updated: 2026-04-01

Phase 2

Dantrolene for Treatment of Hyperthermia in Subarachnoidal Hemorrhage (SAH)

TerminatedNCT00796900

Medical University of ViennaHyperthermia

Start: 2008-05-31End: 2011-03-31Target: 34Updated: 2011-05-12

Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

CompletedNCT01950520

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Healthy Volunteers

Start: 2014-02-07End: 2024-06-11Updated: 2024-10-16

The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery

CompletedNCT03762109

Beth Israel Deaconess Medical CenterLumbar Spine Injury

Start: 2019-07-29End: 2024-06-01Updated: 2024-07-11

Dantrolene in Statin-induced Myopathy

Not yet recruitingNCT06966843

Tanta UniversityStatins Induced Myopathy

Start: 2027-10-31End: 2030-03-31Target: 23Updated: 2025-05-13

Unknown Phase

The clinical test to evaluate the effective and safety dosage of dantrolene for the treatment of ventricular tachycardia in patients with heart disease

RecruitingJPRN-UMIN000004346

Department of Medicine and Clinical Science Yamaguchi UniversityVentricular tachycardia (CPVT, ARVC, Heart failure)

Start: 2010-10-01Target: 5Updated: 2025-07-18

Related Papers

Clemastine fumarate accelerates accumulation of disability in progressive multiple sclerosis by enhancing pyroptosis

Journal of Clinical Investigation2025-05-147 citations

Dantrolene for cerebral vasospasm after subarachnoid haemorrhage: a randomised double blind placebo-controlled safety trial

Journal of Neurology Neurosurgery & Psychiatry2014-10-2417 citations

Effects of a single dose of dantrolene in patients with cerebral vasospasm after subarachnoid hemorrhage: a prospective pilot study.

2011-03-3120 citations