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dalotuzumab

DRUG12 trials

Sponsors

Merck Sharp & Dohme LLC, Alliance for Clinical Trials in Oncology

Conditions

Advanced Solid TumorsBreast CancerBreast NeoplasmsCarcinoma, Non-small-cell LungLung CancerMetastatic Colorectal CancerMultiple MyelomaNeoplasm

Phase 1

Phase 2

Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Metastatic Colorectal Cancer (MK-0646-004)
CompletedNCT00614393
Merck Sharp & Dohme LLCMetastatic Colorectal Cancer
Start: 2007-12-24End: 2012-03-07Updated: 2018-08-08
A Study Evaluating Dalotuzumab (MK-0646) in Combination With Erlotinib for Participants With Non-Small Cell Lung Cancer (MK-0646-007)
CompletedNCT00654420
Merck Sharp & Dohme LLCCarcinoma, Non-small-cell Lung
Start: 2008-03-19End: 2012-02-13Updated: 2018-08-08
Gemcitabine Hydrochloride and Carboplatin With or Without MK-0646 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
WithdrawnNCT00951444
Alliance for Clinical Trials in OncologyLung Cancer
Updated: 2016-07-06
A Study of Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041 AM3)
CompletedNCT01234857
Merck Sharp & Dohme LLCBreast Cancer
Start: 2010-09-17End: 2013-10-15Updated: 2017-05-31
A Phase II Trial of Ridaforolimus and Exemestane, Compared to Ridaforolimus, Dalotuzumab and Exemestane in Participants With Breast Cancer (MK-8669-064)
CompletedNCT01605396
Merck Sharp & Dohme LLCBreast Neoplasms
Start: 2012-07-04End: 2018-03-15Updated: 2019-03-25
A Trial of Dalotuzumab in Combination With Irinotecan Versus Cetuximab and Irinotecan for Participants With Metastatic Rectal Cancers (mRC) (MK-0646-025)
TerminatedNCT01609231
Merck Sharp & Dohme LLCRectal Neoplasms
Start: 2012-07-06End: 2014-12-09Updated: 2020-05-04

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