Dalcetrapib (RO4607381)

DRUG3 trials

Sponsors

Hoffmann-La Roche

Conditions

Coronary Heart Disease

Phase 2

A Long Term Extension of Study NC19453 Evaluating Safety and Efficacy of RO4607381

CompletedNCT00400439

Hoffmann-La RocheCoronary Heart Disease

Start: 2007-01-31End: 2008-01-31Updated: 2020-01-03

A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease

CompletedNCT00655473

Hoffmann-La RocheCoronary Heart Disease

Start: 2008-03-31End: 2010-11-30Updated: 2020-01-03

Phase 3

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

CompletedNCT00658515

Hoffmann-La RocheCoronary Heart Disease

Start: 2008-04-30End: 2012-09-30Updated: 2020-01-03

Related Papers

Future myocardial infarction after an acute coronary syndrome and pharmacogenetic response to dalcetrapib

European Journal of Preventive Cardiology2025-10-131 citations

Association of Lipoprotein(a) With Risk of Recurrent Ischemic Events Following Acute Coronary Syndrome

JAMA Cardiology2017-10-2593 citations

Genotype-Dependent Effects of Dalcetrapib on Cholesterol Efflux and Inflammation

Circulation Cardiovascular Genetics2016-07-1566 citations

Fasting triglycerides predict recurrent ischemic events in patients with acute coronary syndrome treated with statins.

2015-06-01195 citations

Pharmacogenomic Determinants of the Cardiovascular Effects of Dalcetrapib

Circulation Cardiovascular Genetics2015-01-13183 citations

Predictors of change in carotid atherosclerotic plaque inflammation and burden as measured by 18-FDG-PET and MRI, respectively, in the dal-PLAQUE study.

2014-01-2429 citations

СВОБОДНОРАДИКАЛЬНОЕ ОКИСЛЕНИЕ В ИНТАКТНЫХ И АКТИВИРОВАННЫХ ТРОМБОЦИТАХ

Фундаментальные исследования (Fundamental Research)2014-01-01

Relationship of serum inflammatory biomarkers with plaque inflammation assessed by FDG PET/CT: the dal-PLAQUE study.

2013-10-0155 citations

The complementary roles of dynamic contrast-enhanced MRI and 18F-fluorodeoxyglucose PET/CT for imaging of carotid atherosclerosis.

2013-08-1445 citations

Effects of dalcetrapib in patients with a recent acute coronary syndrome.

2012-11-051509 citations

Vascular effects and safety of dalcetrapib in patients with or at risk of coronary heart disease: the dal-VESSEL randomized clinical trial.

2012-02-16165 citations

Safety and efficacy of dalcetrapib on atherosclerotic disease using novel non-invasive multimodality imaging (dal-PLAQUE): a randomised clinical trial.

2011-09-09389 citations