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D001971

2 trials

Sponsors

Tomimoto Hidekazu, Ogawa Koji

Conditions

Alzheimers disease patients with PSEN1 mutations Dementia, Alzheimers disease, familial, genetic, presenilin 1Presenilin1 gene mutation in Alzheimers disease patients Dementia, Alzheimers disease, familial, genetic, presenilin 1

Phase 2

Repurposing bromocriptine for Abeta metabolism in Alzheimer's disease
Active, not recruitingJPRN-jRCT2041200008
Tomimoto HidekazuAlzheimers disease patients with PSEN1 mutations Dementia, Alzheimers disease, familial, genetic, presenilin 1
Start: 2020-06-09Target: 10Updated: 2026-06-29

Phase 3

Double-blind comparative study followed by open-label extension study to evaluate the efficacy and safety of TW-012R in Alzheimer's disease with presenilin 1 mutations(Phase 2/3 Study)
RecruitingJPRN-jRCT2041250040
Ogawa KojiPresenilin1 gene mutation in Alzheimers disease patients Dementia, Alzheimers disease, familial, genetic, presenilin 1
Start: 2025-06-20Target: 24Updated: 2026-06-29

Related Papers

Repurposing bromocriptine for Aβ metabolism in Alzheimer’s disease (REBRAnD) study: randomised placebo-controlled double-blind comparative trial and open-label extension trial to investigate the safety and efficacy of bromocriptine in Alzheimer’s disease with presenilin 1 (PSEN1) mutations
BMJ Open2021-06-0125 citations