D-PLEX
Sponsors
Polypid Ltd., PolyPid Ltd.
Conditions
Abdominal SurgeryCardiac SurgeryColon SurgeryPost-Op InfectionPostoperative Wound Infection Deep Incisional Surgical SitePostoperative Wound Infection Superficial IncisionalPrevention of post abdominal surgery incisional infection.Sternal Infection
Phase 1
Phase 2
Phase 3
D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery
TerminatedNCT03558984
Start: 2019-12-17End: 2022-10-24Updated: 2026-06-30
D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
CompletedNCT04233424
Start: 2020-06-24End: 2022-09-02Updated: 2026-04-21
D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)
CompletedNCT04411199
Start: 2020-12-15End: 2025-05-10Updated: 2026-07-13
Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to Assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SoC), Compared to a SoC Treated Control Arm, in Prevention of Post Abdominal Surgery Incisional Infection.
CompletedCTIS2023-509698-21-00
Start: 2021-03-17End: 2025-05-08Target: 474Updated: 2025-02-24