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d-amphetamine

DRUG10 trials

Sponsors

National Institute on Drug Abuse (NIDA), The University of Texas Health Science Center, Houston, University of Illinois at Chicago, Biotie Therapies Inc., University of Pittsburgh

Conditions

Abuse PotentialAlcohol DependenceAnhedoniaCocaine AbuseCocaine DependenceCocaine Use DisorderCocaine-Related DisordersOpiate Dependence

Early Phase 1

Cocaine Use Disorder and Cortical Dopamine
CompletedNCT03349606
University of PittsburghCocaine Dependence
Start: 2010-06-02End: 2020-06-01Target: 30Updated: 2020-06-04
Brain Mechanisms in Young Adults
CompletedNCT03606473
Gale RichardsonCocaine-Related Disorders
Start: 2018-01-24End: 2020-08-31Updated: 2020-09-03
[C-11]NPA PET-amphetamine in Cocaine Use Disorders
RecruitingNCT05011760
Rajesh NarendranCocaine Use Disorder
Start: 2021-01-31End: 2028-09-01Target: 30Updated: 2025-06-05

Phase 1

A Study to Determine the Abuse Potential of Tozadenant Relative to D-Amphetamine and Placebo When Administered Orally in Healthy, Non-Dependent, Recreational Polydrug Users
TerminatedNCT03200080
Biotie Therapies Inc.Abuse Potential
Start: 2017-09-18End: 2017-11-28Updated: 2018-08-13

Phase 2

Dextroamphetamine-Cocaine Behavioral Intervention - 5
CompletedNCT00000308
National Institute on Drug Abuse (NIDA)Cocaine-Related Disorders
Start: 1995-09-30End: 2000-09-30Updated: 2017-01-12
Dextroamphetamine as an Adjunct in Cocaine Treatment - 1
CompletedNCT00000304
National Institute on Drug Abuse (NIDA)Cocaine-Related Disorders, Substance-Related Disorders
Start: 1997-08-31End: 2001-08-31Updated: 2017-01-12
Targeting Anhedonia in Cocaine Use Disorder
CompletedNCT02773212
University of Illinois at ChicagoAnhedonia, Cocaine-Related Disorders
Start: 2017-02-01End: 2022-04-04Updated: 2024-08-09
Pharmacologic Augmentation of Targeted Cognitive Training in Schizophrenia
CompletedNCT04414930
University of California, San DiegoSchizoaffective Disorder, Schizophrenia
Start: 2020-11-09End: 2024-12-30Updated: 2025-12-17
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
RecruitingNCT05790239
Stephen Robert MarderPost Traumatic Stress Disorder
Start: 2025-03-01End: 2026-03-31Target: 40Updated: 2025-03-28

Unknown Phase

Substance Abuse Pre-Treatment Screening Study
RecruitingNCT00439049
The University of Texas Health Science Center, HoustonAlcohol Dependence, Cocaine Abuse, Cocaine Dependence +2
Start: 2005-10-31End: 2026-06-30Target: 7500Updated: 2023-12-20

Related Papers

Exploring the Role of Reward Functioning in the Overlap of Post-Traumatic Stress and Cocaine Use Disorder.
2025-02-18