Cytokine-Induced Memory-like Natural Killer Cells

BIOLOGICAL3 trials

Sponsors

Washington University School of Medicine, Dana-Farber Cancer Institute

Conditions

Acute Myeloid LeukemiaAcute Myeloid Leukemia RecurrentAdvanced MelanomaClear Cell Ovarian CarcinomaEndometroid Ovarian CarcinomaLeukemiaLeukemia, MyeloidMetastatic Melanoma

Phase 1

Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors

RecruitingNCT05629546

Washington University School of MedicineAdvanced Melanoma, Metastatic Melanoma

Start: 2024-11-06End: 2030-11-30Target: 33Updated: 2025-09-12

CIML NK Cells With Venetoclax for AML

RecruitingNCT06152809

Dana-Farber Cancer InstituteAcute Myeloid Leukemia, Acute Myeloid Leukemia Recurrent, Leukemia +1

Start: 2024-02-20End: 2027-11-30Target: 10Updated: 2026-03-18

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

RecruitingNCT06321484

Dana-Farber Cancer InstituteClear Cell Ovarian Carcinoma, Endometroid Ovarian Carcinoma, Ovarian Cancer +4

Start: 2024-10-09End: 2031-10-31Target: 18Updated: 2026-03-04

Related Papers

Abstract B062: Ascites-derived natural killer (NK) cells exhibit chronic overstimulation and metabolic dysfunction in patients with advanced epithelial ovarian cancer

Cancer Research2025-09-19

Recent Advancements in Cell-Based Therapies in Melanoma.

2024-09-124 citations