Cysteamine Bitartrate

DRUG8 trials

Sponsors

Icahn School of Medicine at Mount Sinai, University of California, San Diego, Hospices Civils de Lyon, Amgen, Children's Hospital Medical Center, Cincinnati

Conditions

AsthmaCystinosisInherited Mitochondrial Disease, Including Leigh SyndromeMajor Depressive DisorderMitochondrial DiseasesNephropathic Cystinosis

Phase 1

Cysteamine for Asthma

CompletedNCT03883984

Children's Hospital Medical Center, CincinnatiAsthma

Start: 2019-06-18End: 2021-02-10Updated: 2021-05-06

PK and PD Study of NPI-001 and Cysteamine Bitartrate

Active, not recruitingNCT05994534

Nacuity Pharmaceuticals, Inc.Cystinosis

Start: 2023-10-29End: 2026-08-01Target: 12Updated: 2026-06-30

Phase 2

Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease

CompletedNCT02023866

AmgenInherited Mitochondrial Disease, Including Leigh Syndrome

Start: 2014-05-31End: 2016-10-31Updated: 2024-12-27

A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease

TerminatedNCT02473445

AmgenMitochondrial Diseases

Start: 2015-05-19End: 2017-03-06Updated: 2024-12-27

Unknown Phase

Cysteamine Therapy for Major Depressive Disorder

TerminatedNCT00715559

Icahn School of Medicine at Mount SinaiMajor Depressive Disorder

Start: 2008-07-31End: 2009-05-31Updated: 2017-04-07

Study in Healthy Adults to Determine the Effect That Food Has on the Absorption and Delivery of the Drug Cystagon™

CompletedNCT01432561

University of California, San DiegoCystinosis, Nephropathic Cystinosis

Start: 2011-09-30End: 2011-12-31Updated: 2013-10-09

A Cohort of Patients With Cystinosis : Compliance to Cysteamine and Neurological Complications

CompletedNCT02012114

Hospices Civils de LyonCystinosis

Start: 2011-12-31End: 2021-12-14Updated: 2025-12-19

Observational Study to Assess the Quality of Life in Nephropathic Cystinosis Patients

Enrolling by invitationNCT04246060

Chiesi SA/NVNephropathic Cystinosis

Start: 2020-07-31End: 2026-07-01Target: 31Updated: 2021-11-29