Cyclosporins

DRUG14 trials

Sponsors

Northwestern University, Fondazione IRCCS Policlinico San Matteo di Pavia, Siriraj Hospital, Merck KGaA, Darmstadt, Germany, Boston Children's Hospital

Conditions

Aplastic AnemiaDrug Interaction PotentiationDry EyeDyskeratosis CongenitaHoyeraal Hreidarsson SyndromeIdiopathic Membranous NephropathyInsulinKeratoconjunctivitis, Vernal

Phase 1

Rheumatoid Arthritis:Tolerance Induction by Mixed Chimerism

TerminatedNCT00282412

Northwestern UniversityRheumatoid Arthritis

Start: 2002-09-30End: 2016-06-30Updated: 2018-07-30

Cyclosporine A in Combination With Nab-Paclitaxel in Patients With Metastatic Breast Cancer

CompletedNCT00983424

Northwestern UniversityMetastatic Breast Cancer

Start: 2010-02-28End: 2013-05-31Updated: 2013-09-16

Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin

CompletedNCT03801746

Akebia TherapeuticsDrug Interaction Potentiation

Start: 2018-07-20End: 2018-08-15Updated: 2019-03-22

Phase 2

Rapamycin and Regulatory T Cells in Kidney Transplantation

CompletedNCT01014234

Fondazione IRCCS Policlinico San Matteo di PaviaKidney Transplantation

Start: 2008-07-31End: 2013-06-30Updated: 2015-03-25

Efficacy Study of FK-506 and Cyclosporine in Vernal Keratoconjunctivits (VKC)

CompletedNCT01068054

Siriraj HospitalKeratoconjunctivitis, Vernal

Start: 2003-06-30End: 2005-05-31Updated: 2010-02-12

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Active, not recruitingNCT01659606

Boston Children's HospitalAplastic Anemia, Dyskeratosis Congenita, Hoyeraal Hreidarsson Syndrome +1

Start: 2012-07-01End: 2034-12-01Target: 40Updated: 2026-03-27

Alipogene Tiparvovec for the Treatment of LPLD Patients

WithdrawnNCT02904772

UniQure Biopharma B.V.LPL Deficiency

Start: 2016-10-31End: 2020-09-30Updated: 2017-08-17

Phase 3

Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndrome

CompletedNCT03865888

Pavly MoawdDry Eye, Sjogren Syndrome

Start: 2018-10-30End: 2019-04-30Updated: 2019-05-22

Phase 4

Study of Therapeutic Options for Subjects Discontinuing Efalizumab and Experiencing Disease Recurrence

CompletedNCT01079988

Merck KGaA, Darmstadt, GermanyPsoriasis

Start: 2004-02-29End: 2005-04-30Updated: 2014-02-27

Mycophenolate Mofetil Plus Steroid in the Treatment Of Patients With Progressive Idiopathic Membranous Nephropathy

Guangdong Provincial People's HospitalIdiopathic Membranous Nephropathy

Start: 2018-07-01End: 2020-12-31Target: 128Updated: 2019-03-18

Clinical Trial To Determine The Effectiveness And Safety Of Topical Insulin In Dry Eye

CompletedNCT05692739

Barbara Burgos BlascoDry Eye, Insulin

Start: 2022-10-19End: 2025-11-05Updated: 2026-03-05

Unknown Phase

Identification and Validation of Functional Biomarkers for Keratoconus

Narayana NethralayaKeratoconus

Start: 2013-04-30End: 2015-12-31Target: 200Updated: 2014-03-06

Economic Evaluation of Systemic Treatments for Moderate-to-severe Psoriasis

CompletedNCT01812954

Jochen Schmitt.Psoriasis

Start: 2013-03-31End: 2014-06-30Updated: 2017-08-11

Clinical Study of Non Severe Aplastic Anemia Treated With Cyclosporine, Androgen and Levamisole

Shengyun LinAplastic Anemia

Start: 2018-01-01End: 2022-07-01Target: 248Updated: 2017-07-26

Related Papers

Evaluation of the effect of topical tacrolimus 0.03% versus cyclosporine 0.05% in the treatment of dry eye secondary to Sjogren syndrome

European Journal of Ophthalmology2021-02-0250 citations

Elevated Expression of Matrix Metalloproteinase-9 and Inflammatory Cytokines in Keratoconus Patients Is Inhibited by Cyclosporine A

Investigative Ophthalmology & Visual Science2015-02-03213 citations