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CYCLOPHOSPHAMIDE MONOHYDRATE

DRUG10 trials

Sponsors

Novartis Pharma AG, CanCell Therapeutics, Nationwide Childrens Hospital, Nationwide Childrens Hospital, Celgene Corp., Istituto Europeo Di Oncologia S.r.l.

Conditions

ANCA-associated Vasculitis (AAV)Acute lymphoblastic leukemiaAdult patients with follicular B-cell non-Hodgkin lymphoma grade 1-3AAdvanced Stage of Hodgkin LymphomaChronic lymphocytic leukemia/Small lymphocytic lymphomaDiffuse large B-Cell lymphomaHigh-Risk large B-Cell lymphomaHigh-risk Large B-cell Lymphoma

Phase 1

Phase 2

Phase 3

A randomized, open-label, multi-center phase III trial comparing tisagenlecleucel to standard of care in adult participants with relapsed or refractory follicular lymphoma
Active, not recruitingCTIS2023-503452-27-00
Novartis Pharma AGAdult patients with follicular B-cell non-Hodgkin lymphoma grade 1-3A, relapsed or refractory after at least two prior lines of systemic therapy
Start: 2024-01-02Target: 64Updated: 2025-04-30
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Golcadomide Plus R-CHOP Chemotherapy vs Placebo Plus R-CHOP Chemotherapy in Participants with Previously Untreated High-risk Large B-cell Lymphoma (GOLSEEK-1)
Active, not recruitingCTIS2023-510178-15-00
Celgene Corp.High-risk Large B-cell Lymphoma
Start: 2024-07-31Target: 322Updated: 2025-09-10
HD21 for advanced stages - Treatment optimization trial in the first-line treatment of advanced stage Hodgkin lymphoma; comparison of 4-6 cycles of escalated BEACOPP with 4-6 cycles of BrECADD
CompletedCTIS2024-518022-33-00
University Of CologneAdvanced Stage of Hodgkin Lymphoma
Start: 2016-07-15End: 2024-12-01Target: 1320Updated: 2024-11-19
A Phase 3, Open-label, Uncontrolled Single-arm Study to Evaluate the Efficacy, Pharmacokinetics, and Safety of Avacopan in Combination With a Rituximab or a Cyclophosphamide-containing Regimen in Children from 6 Years to < 18 Years of Age with Active ANCA-associated Vasculitis (AAV)
RecruitingCTIS2024-514779-16-00
Amgen Inc.ANCA-associated Vasculitis (AAV)
Start: 2025-02-11Target: 11Updated: 2026-01-15
A Global Multicenter, Open Label, Randomized Phase III Confirmatory Study of Lisaftoclax (APG-2575) in Combination with Acalabrutinib versus Immunochemotherapy in Patients with Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (GLORA-2 Study)
RecruitingCTIS2024-514084-26-00
Ascentage Pharma Group Inc.Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Start: 2025-08-22Target: 29Updated: 2025-07-31

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