Cyclin-Dependent Kinase 4 Inhibitor

DRUG2 trials

Sponsors

University of Washington, SWOG Cancer Research Network

Conditions

Anatomic Stage IV Breast Cancer AJCC v8Metastatic HER2-Negative Breast CarcinomaMetastatic HER2-Positive Breast CarcinomaMetastatic Hormone Receptor-Positive Breast CarcinomaOligometastatic Breast Carcinoma

Phase 2

A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

RecruitingNCT07112053

University of WashingtonAnatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Negative Breast Carcinoma, Metastatic Hormone Receptor-Positive Breast Carcinoma

Start: 2025-11-17End: 2028-12-31Target: 40Updated: 2026-04-06

Phase 3

Adding Surgery and Radiation to the Usual Treatment for HER2-Positive Breast Cancer That Had Already Spread at Diagnosis

Not yet recruitingNCT07578116

SWOG Cancer Research NetworkAnatomic Stage IV Breast Cancer AJCC v8, Metastatic HER2-Positive Breast Carcinoma, Oligometastatic Breast Carcinoma

Start: 2027-03-09End: 2033-05-31Target: 562Updated: 2026-05-11