Cx601

DRUG3 trials

Sponsors

Tigenix S.A.U.

Conditions

Anal FistulaCrohn's Disease

Phase 1

Study to Assess the Safety and Efficacy of Expanded Allogenic Adipose-derived Stem Cells (eASCs) (Cx601), for Treatment of Complex Perianal Fistulas in Perianal Crohn's Disease.

CompletedNCT01372969

Tigenix S.A.U.Anal Fistula, Crohn's Disease

Start: 2009-06-30End: 2010-09-30Updated: 2019-04-12

Phase 3

Adipose Derived Mesenchymal Stem Cells for Induction of Remission in Perianal Fistulizing Crohn's Disease

CompletedNCT01541579

Tigenix S.A.U.Crohn's Disease

Start: 2012-07-31End: 2016-11-30Target: 278Updated: 2019-11-29

Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

CompletedNCT03279081

Tigenix S.A.U.Crohn's Disease

Start: 2017-09-15End: 2023-07-26Updated: 2024-09-19

Related Papers

Darvadstrocel in Patients With Crohn's Disease With Complex Perianal Fistulas: The ADMIRE CD II Phase 3 Randomized Trial.

2026-03-06

Follow-up Study to Evaluate the Long-term Safety and Efficacy of Darvadstrocel (Mesenchymal Stem Cell Treatment) in Patients With Perianal Fistulizing Crohn’s Disease: ADMIRE-CD Phase 3 Randomized Controlled Trial

Diseases of the Colon & Rectum2021-12-10125 citations

P436 Darvadstrocel treatment outcomes in Crohn’s disease patients with complex perianal fistulas: the role of TNFi co-treatment in ADMIRE CD

Journal of Crohn s and Colitis2019-01-251 citations

Long-term Efficacy and Safety of Stem Cell Therapy (Cx601) for Complex Perianal Fistulas in Patients With Crohn's Disease.

2017-12-24323 citations

OP009 Long-term efficacy and safety of Cx601, allogeneic expanded adipose-derived mesenchymal stem cells, for complex perianal fistulas in Crohn's disease: 52-week results of a phase III randomised controlled trial

Journal of Crohn s and Colitis2017-01-266 citations

Expanded allogeneic stem cells (Cx601) for complex perianal fistulas in Crohn’s disease: a phase 3 randomised, double-blinded controlled trial

Côlon & Rectum2017-01-051 citations

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial.

2016-07-29743 citations