Curative Surgery

PROCEDURE4 trials

Conditions

Biliary Tract CancerBreast CancerBreast Cancer FemaleBreast Cancer, MaleCholangiocarcinomaGall Bladder CarcinomaHER2 Positive Breast CarcinomaHER2-positive Breast Cancer

Early Phase 1

HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer

CompletedNCT03387553

H. Lee Moffitt Cancer Center and Research InstituteBreast Cancer, Breast Cancer Female, Breast Cancer, Male +5

Start: 2018-06-06End: 2026-02-19Updated: 2026-05-07

Phase 2

CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrence

RecruitingNCT06037980

Gruppo Oncologico del Nord-OvestBiliary Tract Cancer, Cholangiocarcinoma

Start: 2023-11-07End: 2029-01-01Target: 300Updated: 2026-09-09

Phase 3

Neoadjuvant Chemotherapy for Locally Advanced Gall Bladder Cancer : a Randomized Control Trial (NEOGB)

RecruitingNCT06712420

Rajiv Gandhi Cancer Institute & Research Center, IndiaGall Bladder Carcinoma

Start: 2025-01-01End: 2028-12-31Target: 114Updated: 2025-04-16

Unknown Phase

Does Timing of Completion Radical Cholecystectomy Determine the Survival in Incidental Carcinoma Gallbladder

CompletedNCT05114369

Sanjay Gandhi Postgraduate Institute of Medical SciencesGall Bladder Carcinoma, Survival

Start: 2009-01-01End: 2021-10-01Updated: 2021-11-10

2026-05-13

A pilot study incorporating HER2-directed dendritic cells into neoadjuvant therapy of early stage HER2+ER- breast cancer

npj Breast Cancer2025-03-175 citations

BSLM-07 A FIRST IN HUMAN PHASE 1 TRIAL OF DOSE ESCALATING INTRATHECAL (IT) DENDRITIC CELLS (CDC1S) PRIMED AGAINST HER2/HER3 IN PATIENTS (PTS) WITH LEPTOMENINGEAL DISEASE (LMD) FROM TRIPLE NEGATIVE (TNBC) OR HER2+ BREAST CANCER (BC)

Neuro-Oncology Advances2024-08-011 citations

A first-in-human phase 1 trial of dose escalating intrathecal (IT) dendritic cells (cDC1s) primed against HER2/HER3 in patients (pts) with leptomeningeal disease (LMD) from triple-negative (TNBC) or HER2+ breast cancer (BC).

Journal of Clinical Oncology2024-06-011 citations

A phase II/III randomized clinical trial of CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative chemotherapy versus immediate resection in patIents with resecTable BiliarY Tract Cancers (BTC) at high risk for recurrence: PURITY study.

2024-04-0814 citations