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DRUG10 trials

Conditions

Acute Lymphoblastic LeukemiaAcute Lymphocytic LeukemiaAdult Lymphoblastic LymphomaAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisBreast CancerBreast Cancer ModelEarly Breast CancerEffects of Chemotherapy

Phase 1

Targeting the Tumor Microenvironment in R/M SCCHN

NCT03844763

Gruppo Oncologico del Nord-OvestHead and Neck Cancer

Start: 2019-01-07End: 2024-06-30Target: 71Updated: 2020-03-03

Phase 2

Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphoma

TerminatedNCT02043587

University of California, San DiegoAcute Lymphocytic Leukemia, Adult Lymphoblastic Lymphoma

Start: 2014-01-31End: 2022-04-14Updated: 2022-05-02

Clinical Study of XPO-1 Inhibitors Plus CAR-T Cells in Relapsed Refractory B-cell Non-Hodgkin's Lymphoma

NCT05322330

The First Affiliated Hospital of Soochow UniversityRelapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Start: 2022-02-10End: 2024-02-10Target: 20Updated: 2023-02-09

Phase 3

PERS Genetic Model Assistant Decision-making System of Neoadjuvant Chemotherapy for Breast Cancer

NCT03006614

Shi YanxiaBreast Cancer, Breast Cancer Model, Effects of Chemotherapy

Start: 2016-04-30End: 2023-03-31Target: 320Updated: 2017-01-16

Cardiac Safety and Efficacy for Early-stage Breast Cancer Patients Treated With Pegylated Liposomal Doxorubicin（PLD)

NCT03949634

Fudan UniversityEarly Breast Cancer

Start: 2017-09-01End: 2020-10-31Target: 272Updated: 2019-05-14

Carboplatin Intensified Chemotherapy for TRIple NEgative Breast Cancer(CITRINE)

Active, not recruitingNCT04296175

Fudan UniversityTriple-negative Breast Cancer

Start: 2020-03-05End: 2027-03-31Target: 808Updated: 2025-03-26

Phase 4

HD-Idarubicin/Etoposide Intensified Conditioning Regimen Allo-HSCT for Adult ALL

NCT01873807

Nanfang Hospital, Southern Medical UniversityAcute Lymphoblastic Leukemia

Start: 2013-05-31End: 2015-12-31Target: 100Updated: 2015-10-09

PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis

NCT03689465

Nanfang Hospital, Southern Medical UniversityHematopoietic Stem Cell Transplantation

Start: 2018-10-29End: 2020-12-31Target: 260Updated: 2019-10-28

Unknown Phase

The Clinical Efficacy of DFPP in Patients With AAGN

TerminatedNCT02294344

Zhi-Hong Liu, M.D.Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

Start: 2014-06-30End: 2017-04-30Updated: 2018-02-06

Comparing Intermediate-dose CTX+ G-CSF Plus or Not rhTPO for PB CD34+ Cells Mobilization in MM Patients

NCT02572596

Wang GuorongMultiple Myeloma

Start: 2013-01-01End: 2018-12-31Target: 200Updated: 2017-02-09

Clinical Cancer Research2026-02-17

Effect of adjuvant carboplatin intensified chemotherapy versus standard chemotherapy on survival in women with high risk, early stage, triple negative breast cancer (CITRINE): randomised, open label phase 3 trial.

2025-12-23

Pegylated liposomal doxorubicin + cyclophosphamide followed by taxane as adjuvant therapy for early-stage breast cancer: a randomized controlled trial

The Oncologist2025-06-011 citations

Intensive chemotherapy versus standard chemotherapy among patients with high risk, operable, triple negative breast cancer based on integrated mRNA-lncRNA signature (BCTOP-T-A01): randomised, multicentre, phase 3 trial

BMJ2024-10-2314 citations

PB2289: PRELIMINARY DATA FROM A FIRST-IN HUMAN PHASE II STUDY OF SEQUENTIAL USE OF SELINEXOR AND CD19 CHIMERIC ANTIGEN RECEPTOR MODIFIED T-CELL THERAPY (CART19) IN PATIENTS WITH RELAPSED OR REFRACTORY B-CELL NON-HODGKIN LYMPHOMA

HemaSphere2023-08-01

Cardiac safety and efficacy for patients with early-stage breast cancer treated with pegylated liposomal doxorubicin (PLD) or doxorubicin.

Journal of Clinical Oncology2023-06-011 citations

PRELIMINARY DATA FROM A FIRST‐IN HUMAN PHASE II STUDY OF SEQUENTIAL USE OF SELINEXOR AND CD19 CART THERAPY IN PATIENTS WITH RELAPSED OR REFRACTORY B‐CELL NON‐HODGKIN LYMPHOMA

Hematological Oncology2023-06-011 citations

A Phase II Study of Pegylated Asparaginase, Cyclophosphamide, Rituximab, and Dasatinib Added to the UCSF 8707 (Linker 4-drug) Regimen with Liposomal Cytarabine CNS Prophylaxis for Adults with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL): University of California Hematologic Malignancies Consortium Study (UCHMC) 1401

Blood2018-11-297 citations

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