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CT-guided Stereotactic Body Radiation Therapy

RADIATION3 trials

Sponsors

Jonsson Comprehensive Cancer Center

Conditions

Localized Prostate AdenocarcinomaProstate AdenocarcinomaStage I Prostate Cancer AJCC v8Stage II Prostate Cancer AJCC v8Stage III Prostate Cancer AJCC v8

Unknown Phase

CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer, MIRAGE Study
Active, not recruitingNCT04384770
Jonsson Comprehensive Cancer CenterProstate Adenocarcinoma
Start: 2020-05-12End: 2028-04-01Updated: 2026-05-11
Computed Tomography-Guided Stereotactic Body Radiation Therapy With Intrafraction Motion Monitoring for the Treatment of Localized Prostate Cancer, ILLUSION Trial
Active, not recruitingNCT06995053
Jonsson Comprehensive Cancer CenterLocalized Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 +1
Start: 2025-06-27End: 2036-09-01Target: 91Updated: 2026-08-20
Image-Guidance and Online Adaptation With Stereotactic Body Radiation Therapy for the Treatment of Localized Prostate Cancer, MANTICORE Trial
RecruitingNCT07276438
Jonsson Comprehensive Cancer CenterLocalized Prostate Adenocarcinoma, Stage III Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8 +1
Start: 2025-12-01End: 2032-12-31Target: 186Updated: 2026-02-05

Related Papers

Dosimetric Comparison of Magnetic Resonance Imaging Guided Versus Reduced Margin Computed Tomography Guided Stereotactic Body Radiation Therapy for Localized Prostate Cancer: Post Hoc Analysis of a Phase 3 Trial.
2025-06-05
Validation and Derivation of miRNA-Based Germline Signatures Predicting Radiation Toxicity in Prostate Cancer.
2025-06-011 citations
Magnetic Resonance Imaging Versus Computed Tomography Guidance for Stereotactic Body Radiotherapy in Prostate Cancer: 2-year Outcomes from the MIRAGE Randomized Clinical Trial
European Urology2024-11-1321 citations
PROSTOX, a signature of late GU toxicity after SBRT radiotherapy in MIRAGE, a prospective trial.
Journal of Clinical Oncology2024-06-01
(016) Sexual Health Toxicity Following MRI-Guided versus CT-guided Prostate SBRT
The Journal of Sexual Medicine2024-02-01
Quantifying Intrafraction Motion and the Impact of Gating for Magnetic Resonance Imaging-Guided Stereotactic Radiation therapy for Prostate Cancer: Analysis of the Magnetic Resonance Imaging Arm From the MIRAGE Phase 3 Randomized Trial.
2023-12-3014 citations
Dosimetric predictors for genitourinary toxicity in MR‐guided stereotactic body radiation therapy (SBRT): Substructure with fraction‐wise analysis
Medical Physics2023-12-066 citations
Magnetic Resonance Imaging–Guided vs Computed Tomography–Guided Stereotactic Body Radiotherapy for Prostate Cancer
JAMA Oncology2023-01-12267 citations
Magnetic resonance imaging-guided versus computed tomography-guided stereotactic body radiotherapy for prostate cancer (MIRAGE): Interim analysis of a phase III randomized trial.
Journal of Clinical Oncology2022-02-1630 citations
Magnetic resonance imaging-guided stereotactic body radiotherapy for prostate cancer (mirage): a phase iii randomized trial
BMC Cancer2021-05-1144 citations