Crocin

DRUG5 trials

Sponsors

Mashhad University of Medical Sciences, National Nutrition and Food Technology Institute, Shiraz University of Medical Sciences, Qilu Hospital of Shandong University, Mei Zhang

Conditions

Breast CancerChorioretinopathy, Central SerousOsteoarthritis, KneeType 2 Diabetes

Phase 1

Crocin Supplementation in CSCR

Shiraz University of Medical SciencesChorioretinopathy, Central Serous

Start: 2021-07-01End: 2021-11-30Target: 40Updated: 2021-10-28

Phase 3

Evaluation Effect of Crocina on The Cellular Immune Responses in Osteoarthritis Patients

Mashhad University of Medical SciencesOsteoarthritis, Knee

Start: 2016-07-20End: 2018-07-30Target: 40Updated: 2017-12-18

Unknown Phase

The Effects of Crocin Supplementation on Metabolic Parameters, Oxidative Stress, AMP- Activated Protein Kinase and Inflammation-promoting Genes Expression in Peripheral Blood Mononuclear Cells in Patients With Type 2 Diabetes

CompletedNCT04163757

National Nutrition and Food Technology InstituteType 2 Diabetes

Start: 2019-01-20End: 2019-06-03Updated: 2019-11-15

Protection of Cardiovascular Function With Crocin in BrEast Cancer Patients Undergoing Radiotherapy and Chemotherapy

Qilu Hospital of Shandong UniversityBreast Cancer

Start: 2021-03-29End: 2023-09-25Target: 120Updated: 2022-09-22

Follow up Study of Crocin on Cardiac Function Protection in Patients With Breast Cancer Undergoing Neoadjuvant Chemotherapy Based on Color Doppler Ultrasound Combined With Myocardial Zymogram

Active, not recruitingNCT06187818

Mei ZhangBreast Cancer

Start: 2023-09-01End: 2026-09-01Target: 120Updated: 2024-01-03

Related Papers

Short‐Term, Cycle‐Synchronized Adjunctive Therapy With Crocus Total Glucosides Tablets for Cardiac Protection Against Cancer Therapy‐Related Cardiac Dysfunction in Breast Cancer Patients: A Randomized, Double‐Blind, Placebo‐Controlled Trial

MedComm2026-05-28

Significant Effect of Crocin on the Gene Expression of MicroRNA-21 and MicroRNA-155 in Patients with Osteoarthritis

Iranian Journal of Allergy Asthma and Immunology2022-06-218 citations

A Significant Increase in the Gene Expression of GATA-3 Following the Treatment of Osteoarthritis Patients with Crocin

Iranian Journal of Allergy Asthma and Immunology2022-02-084 citations

The effect of crocin supplementation on glycemic control, insulin resistance and active AMPK levels in patients with type 2 diabetes: a pilot study.

2020-07-0939 citations