Controlled Human Malaria Infection

BIOLOGICAL3 trials

Sponsors

Radboud University Medical Center, Centre de Recherche Médicale de Lambaréné

Conditions

MalariaMalaria (Plasmodium Falciparum)Plasmodium Falciparum

Phase 1

Controlled Human Malaria Infection by Mosquito Bites Using a Local Strain of Plasmodium Falciparum

CompletedNCT07816497

Centre de Recherche Médicale de LambarénéMalaria (Plasmodium Falciparum)

Start: 2025-07-18End: 2026-02-19Updated: 2026-09-11

Unknown Phase

Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis

CompletedNCT01422954

Radboud University Medical CenterMalaria, Plasmodium Falciparum

Start: 2012-01-31End: 2013-04-30Updated: 2013-04-29

Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis

CompletedNCT02080026

Radboud University Medical CenterMalaria

Start: 2014-06-30End: 2015-07-31Updated: 2015-08-10

Related Papers

Sporozoite Immunization of Human Volunteers under Mefloquine Prophylaxis Is Safe, Immunogenic and Protective: A Double-Blind Randomized Controlled Clinical Trial

PLoS ONE2014-11-1450 citations