control group:Sham-control + Basic drug treatment

A prospective, multicenter, randomized, blinded, parallel-controlled clinical trial on the efficacy and safety of bronchoscopic cryoablation denervation with airway cryotherapy system for treatment of severe asthma in adults

A prospective, multicenter, randomized, controlled, superiority-designed clinical trial to evaluate the efficacy and safety of spray cryoablation system in treatment of chronic obstructive pulmonary disease