Combined dexmedetomidine-esketamine administration

DRUG3 trials

Sponsors

Peking University First Hospital

Conditions

AnxietyDepressive SymptomsDexmedetomidineEsketaminePain IntensityPostoperative AnalgesiaSpinal SurgeryUreteral Stricture

Phase 4

Dexmedetomidine-esketamine Combination and Chronic Postsurgical Pain After Spinal Surgery

Not yet recruitingNCT07525999

Peking University First HospitalDexmedetomidine, Esketamine, Pain Intensity +2

Start: 2026-04-01End: 2027-12-01Target: 274Updated: 2026-04-16

Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery

Not yet recruitingNCT07523321

Peking University First HospitalDexmedetomidine, Esketamine, Pain Intensity +2

Start: 2026-04-01End: 2027-05-01Target: 274Updated: 2026-04-14

Dexmedetomidine-Esketamine Combination on Depression and Anxiety After Laparoscopic Ureteral Reconstruction

Not yet recruitingNCT07753772

Peking University First HospitalAnxiety, Depressive Symptoms, Dexmedetomidine +2

Start: 2026-08-01End: 2029-08-01Target: 658Updated: 2026-08-14