COMBINATIONS EXCL. PSYCHOLEPTICS
Sponsors
Merck Sharp & Dohme LLC
Conditions
Endometrial cancerMetastatic non-small cell lung cancer (NSCLC)Non-small Cell Lung Cancer (NSCLC)
Phase 3
A Randomized, Open-label, Phase 3 Study of MK-2870 vs Chemotherapy (Docetaxel or Pemetrexed) in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) with EGFR Mutations or Other Genomic Alterations
RecruitingCTIS2023-503539-16-00
Start: 2025-11-11Target: 104Updated: 2025-11-17
A Phase 3, Randomized, Active-controlled, Open-label, Multicenter Study to Compare the Efficacy and Safety of MK-2870 Monotherapy Versus Treatment of Physician’s Choice in Participants With Endometrial Cancer Who Have Received Prior Platinum-based Chemotherapy and Immunotherapy (MK-2870-005/ENGOT-en23/GOG-3095)
Active, not recruitingCTIS2023-504816-14-00
Start: 2024-03-08Target: 378Updated: 2025-09-04
A Randomized, Open-label, Phase 3 Study of MK-2870 in Combination With Pembrolizumab Compared to Pembrolizumab Monotherapy in the First-line Treatment of Participants With Metastatic Non-small Cell Lung Cancer With PD-L1 TPS Greater than or Equal to 50% (TroFuse-007)
RecruitingCTIS2023-503376-24-00
Start: 2024-03-20Target: 196Updated: 2025-12-01