Combination Agent 1

BIOLOGICAL2 trials

Sponsors

Avenzo Therapeutics, Inc., Pfizer

Conditions

Advanced/Metastatic Non-Small Cell Lung CancerBiliary Tract Cancer (BTC)Carcinoma, Non-Small Cell LungEpithelial TumorLocally AdvancedLung CancersMetastatic Solid TumorsNasopharyngeal Cancers

Phase 1

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingNCT07038343

Avenzo Therapeutics, Inc.Biliary Tract Cancer (BTC), Epithelial Tumor, Locally Advanced +5

Start: 2025-06-04End: 2030-12-01Target: 480Updated: 2026-05-13

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

RecruitingNCT07227298

PfizerAdvanced/Metastatic Non-Small Cell Lung Cancer, Carcinoma, Non-Small Cell Lung, Non-Small Cell Lung Cancer

Start: 2026-01-30End: 2033-08-23Target: 162Updated: 2026-04-20