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Colchicine 0.5 MG Oral Tablet Once Daily

DRUG4 trials

Sponsors

Dongying Zhang, Shanghai Tongji Hospital, Tongji University School of Medicine, Duke University, Shin Kong Wu Ho-Su Memorial Hospital

Conditions

ACS - Acute Coronary SyndromeChronic InflammationChronic Limb-Threatening IschemiaColchicineCoronary Artery Disease ProgressionCoronary Artery Disease Risk Factors MultipleHeart FailureHeart Failure with Preserved Ejection Fraction (HFPEF)

Phase 3

PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis
Not yet recruitingNCT07232069
Duke UniversityCoronary Artery Disease Progression, Coronary Artery Disease Risk Factors Multiple, Premature Atherosclerosis +1
Start: 2026-07-01End: 2031-07-01Target: 1500Updated: 2026-02-27
Colchicine in Chronic Limb-Threatening Ischemia
Not yet recruitingNCT07536373
Shin Kong Wu Ho-Su Memorial HospitalChronic Limb-Threatening Ischemia
Start: 2026-04-15End: 2030-04-01Target: 200Updated: 2026-04-17

Phase 4

Colchicine in Patients with Heart Failure with Preserved Ejection Fraction and Inflammation
Not yet recruitingNCT06604611
Dongying ZhangChronic Inflammation, Colchicine, Heart Failure +2
Start: 2024-10-31End: 2026-03-31Target: 200Updated: 2024-09-19

Unknown Phase

Multi-omics Characterization and Model Construction of Colchicine Anti-inflammatory Therapy Efficacy in ACS Patients
RecruitingNCT07064109
Shanghai Tongji Hospital, Tongji University School of MedicineACS - Acute Coronary Syndrome
Start: 2025-07-01End: 2027-07-01Target: 380Updated: 2025-09-15