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CO-TRIMOXAZOLE

DRUG8 trials

Sponsors

University Medical Center Utrecht, Assistance Publique Hopitaux De Paris, Fondazione Gimema Franco Mandelli Onlus, University Medical Center Groningen, Oxford University Clinical Research Unit, Vietnam

Conditions

COVID-19 PneumoniaIntensive CarePneumocystis PneumoniaPulmonary Disease Due to Mycobacteria (Diagnosis)Staphylococcus aureus bacteremiaTuberculosisUndifferentiated Febrile IllnessVentilator-associated Pneumonia

Phase 2

Pharmacokinetic Parameters of Co-trimoxazole
CompletedNCT01832987
University Medical Center GroningenTuberculosis
Start: 2013-10-31End: 2014-08-31Updated: 2014-09-16
Finding the Optimal Regimen for Mycobacterium Abscessus Treatment
RecruitingNCT04310930
The University of QueenslandPulmonary Disease Due to Mycobacteria (Diagnosis)
Start: 2020-03-02End: 2030-06-30Target: 300Updated: 2025-08-13
The Role of High Dose Co-trimoxazole in Severe Covid-19 Patients
CompletedNCT04884490
Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshCOVID-19 Pneumonia
Start: 2021-05-15End: 2021-11-14Updated: 2025-03-26
Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults
RecruitingNCT05835479
Mundipharma Research LimitedPneumocystis Pneumonia
Start: 2023-11-14End: 2025-08-31Target: 50Updated: 2025-04-03
Daratumumab in adults with Very High-Risk T-Lineage Acute Lymphoblastic Leukemia (ALL) Treated According to the ALL National Treatment Program (DARATALL-VHR)- GIMEMA ALL3024
RecruitingCTIS2024-511627-34-00
Fondazione Gimema Franco Mandelli OnlusVery High-Risk T-Lineage Acute Lymphoblastic Leukemia (ALL)
Start: 2024-10-17Target: 31Updated: 2025-12-23

Phase 3

Nepal Undifferentiated Febrile Illness Trial
CompletedNCT02773407
Oxford University Clinical Research Unit, VietnamUndifferentiated Febrile Illness
Start: 2016-05-23End: 2019-08-04Updated: 2023-12-06
COTRIVAP - Efficacy of cotrimoxazole as a de-escalation treatment of Ventilator-Associated Pneumonia in intensive care unit. Multicentric non-inferiority randomised controlled trial
CompletedCTIS2023-505108-52-00
Assistance Publique Hopitaux De ParisIntensive Care, Ventilator-associated Pneumonia
Start: 2023-12-20End: 2025-09-19Target: 628Updated: 2025-04-23

Phase 4

Staphylococcus aureus Network Adaptive Platform trial (SNAP)
RecruitingCTIS2023-503582-35-00
University Medical Center UtrechtStaphylococcus aureus bacteremia
Start: 2023-10-26Target: 2348Updated: 2026-01-08

Related Papers

Finding the optimal regimen for <i>Mycobacteroides abscessus</i> treatment (FOR<i>Ma</i>T) in people with <i>Mycobacteroides abscessus</i> pulmonary disease: a multicentre, randomised, multi-arm, adaptive platform trial
BMJ Open2025-09-015 citations
Digital Twins As Control Groups to Accelerate Assessment of Safety and Efficacy of Novel Treatment Strategies in Ph-Negative Acute Lymphoblastic Leukemia
Blood2024-11-05
Trimethoprim-sulfamethoxazole Versus Azithromycin for the Treatment of Undifferentiated Febrile Illness in Nepal: A Double-blind, Randomized, Placebo-controlled Trial
Clinical Infectious Diseases2020-09-255 citations
Co-trimoxazole versus azithromycin for the treatment of undifferentiated febrile illness in Nepal: study protocol for a randomized controlled trial.
2017-10-025 citations
Pharmacokinetic Evaluation of Sulfamethoxazole at 800 Milligrams Once Daily in the Treatment of Tuberculosis
Antimicrobial Agents and Chemotherapy2016-04-1217 citations