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Clopidogrel Tablets

DRUG3 trials

Sponsors

Gyeongsang National University Hospital, Jiangsu vcare pharmaceutical technology co., LTD

Conditions

Acute Coronary SyndromeClopidogrel, Poor Metabolism ofCoronary Artery DiseasePlatelet DysfunctionStent Thrombosis

Phase 1

PK/PD Study of Vicagrel and Clopidogrel in Healthy Subjects With Different CYP2C19 Metabolizers
CompletedNCT05162053
Jiangsu vcare pharmaceutical technology co., LTDAcute Coronary Syndrome
Start: 2021-12-09End: 2022-11-03Updated: 2023-11-03
Pharmacokinetic/Pharmacodynamic Study of Vicagrel Capsules and Clopidogrel Tablets in Healthy CYP2C19 Normal Metabolizers
CompletedNCT07067775
Jiangsu vcare pharmaceutical technology co., LTDAcute Coronary Syndrome
Start: 2025-08-05End: 2025-08-22Updated: 2025-09-09

Unknown Phase

PTRG-DES Consortium
CompletedNCT04734028
Gyeongsang National University HospitalClopidogrel, Poor Metabolism of, Coronary Artery Disease, Platelet Dysfunction +1
Start: 2003-07-09End: 2020-06-30Updated: 2022-03-31

Related Papers

Drug‐Coated Balloon‐Based Strategy for De Novo Coronary Artery Disease Across Complex and High‐Risk Indicated Percutaneous Coronary Intervention Risk Categories: A Multicenter Registry Study
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Sex Differences in Prognostic Implications of CYP2C19 Genotype After Drug-Eluting Stent Implantation.
2026-04-28
Long-Term Impact of Platelet Reactivity and Clinical Risk on Clinical Outcomes in Patients With Coronary Artery Disease: Analysis of the PTRG-DES Registry
Circulation Cardiovascular Interventions2025-09-22
Prognostic Impact of <i>CYP2C19</i> Genotypes on Long‐Term Clinical Outcomes in Older Patients After Percutaneous Coronary Intervention
Journal of the American Heart Association2024-05-181 citations
Different association of atherogenic index of plasma with the risk of high platelet reactivity according to the presentation of acute myocardial infarction
Scientific Reports2024-05-136 citations
High platelet reactivity strongly predicts early stent thrombosis in patients with drug-eluting stent implantation.
2024-01-043 citations
Effect of Calcium Channel Blockers on Antiplatelet Activity of Clopidogrel in Patients Undergoing Percutaneous Coronary Intervention: Insights from the PTRG-DES Consortium
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Prognostic Implication of Platelet Reactivity According to Procedural Complexity After PCI: Subanalysis of PTRG-DES Consortium.
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Implication of diabetic status on platelet reactivity and clinical outcomes after drug-eluting stent implantation: results from the PTRG-DES consortium.
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Drug-coated balloon-based versus drug-eluting stent-only revascularization in patients with diabetes and multivessel coronary artery disease.
2023-05-2018 citations
Sex Differences in Midterm Prognostic Implications of High Platelet Reactivity After Percutaneous Coronary Intervention With Drug‐Eluting Stents in East Asian Patients: Results From the PTRG‐DES (Platelet Function and Genotype‐Related Long‐Term Prognosis in Drug‐Eluting Stent–Treated Patients With Coronary Artery Disease) Consortium
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Clinical Impact of CYP2C19 Genotype on Clopidogrel-Based Antiplatelet Therapy After Percutaneous Coronary Intervention.
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Platelet Reactivity and Clinical Outcomes After Drug-Eluting Stent Implantation: Results From the PTRG-DES Consortium.
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Platelet Function and Genotype after DES Implantation in East Asian Patients: Rationale and Characteristics of the PTRG-DES Consortium.
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