CliniMACS CD34 Reagent System

DEVICE7 trials

Sponsors

Indiana University School of Medicine, Everett Meyer, Baylor College of Medicine, Joanne Kurtzberg, MD, Joseph Antin

Conditions

Acute LeukemiaAcute Lymphoblastic Leukemia (ALL)Acute Myelogenous Leukemia (AML)Advanced Hematologic MalignanciesAllogeneicAllogeneic Hematopoietic Cell Transplantation (HCT)Anemia Due to Disturbance of Proliferation and/or Differentiation of Hematopoietic Stem CellsBenign Neoplasm

Phase 1

A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies

TerminatedNCT00569179

Indiana University School of MedicineLeukemia, Lymphoid, Leukemia, Myelogenous, Chronic, Leukemia, Myeloid, Acute +1

Start: 2007-08-31End: 2010-12-31Updated: 2015-08-31

Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells

TerminatedNCT01050764

Everett MeyerAcute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Chronic Lymphocytic Leukemia (CLL) +4

Start: 2009-06-30End: 2014-06-30Updated: 2018-06-27

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Active, not recruitingNCT05088356

Stanford UniversityAcute Leukemia, Advanced Hematologic Malignancies, Allogeneic Hematopoietic Cell Transplantation (HCT) +3

Start: 2021-09-07End: 2028-05-01Updated: 2026-05-12

Unknown Phase

Ex Vivo T-Cell Depletion of Mobilized Peripheral Blood Stem Cells Via CD34-Selection

RecruitingNCT01189786

Baylor College of MedicineAllogeneic, Stem Cell Transplant

Start: 2010-10-31End: 2027-11-30Target: 241Updated: 2025-12-03

Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood Transplants

Joanne Kurtzberg, MDHematologic Malignancies, Immune Deficiencies, Inborn Errors of Metabolism Disorders

Updated: 2025-11-20

CliniMACS® CD34+ Reagent System for Expanded Access Use

Joseph AntinAnemia Due to Disturbance of Proliferation and/or Differentiation of Hematopoietic Stem Cells, Delayed Graft Function, Graft Failure +1

Start: 2013-03-31Updated: 2016-11-21

Bone Marrow Transplantation Using CD34-Selected Stem Cells From Related or Unrelated Donors in Treating Participants With Cancer or Other Disorders

OHSU Knight Cancer InstituteBenign Neoplasm, Bone Marrow Transplantation Recipient, Hematopoietic Cell Transplantation Recipient +1

Updated: 2026-07-27