Citrate

DRUG5 trials

Sponsors

University Medical Center, Tuzla, Ziekenhuis Oost-Limburg, University Hospital Muenster, Assistance Publique - Hôpitaux de Paris, Albert Schweitzer Ziekenhuis

Conditions

Acute Kidney InjuryBacteremiaCritically IllRenal Replacement Therapybleeding and clotting hemodialysis

Phase 3

Citrate Anticoagulation in Renal Replacement Therapy: Impact of a High Post-filter Calcium Target on Efficacy

CompletedNCT05814341

Assistance Publique - Hôpitaux de ParisRenal Replacement Therapy

Start: 2023-07-01End: 2024-12-15Updated: 2025-08-22

Phase 4

Investigating Different Anticoagulants for Renal Replacement Therapy

CompletedNCT02669589

University Hospital MuensterAcute Kidney Injury

Start: 2016-03-31End: 2020-01-03Updated: 2020-02-19

Unknown Phase

Central Venous Catheter Lock Solution

University Medical Center, TuzlaBacteremia

Start: 2009-04-30Target: 40Updated: 2009-03-17

Magnesium Balance of Citrate-based Continuous Venovenous Hemofiltration, Effect of Citrate Dose.

CompletedNCT02194569

Ziekenhuis Oost-LimburgAcute Kidney Injury, Critically Ill

Start: 2014-07-31End: 2017-06-30Updated: 2018-04-02

A pilot study regarding regional anticoagulation by a citrate containing dialysis fluid.

Active, not recruitingNL-OMON41845

Albert Schweitzer Ziekenhuisbleeding and clotting hemodialysis

Start: 2016-01-01Target: 12Updated: 2024-02-28

Related Papers

Impact of increasing post-filter ionised calcium target on regional citrate anticoagulation efficacy in ICU continuous renal replacement therapy: the non-inferiority randomised controlled Ca-CIBLE protocol

BMJ Open2024-09-011 citations

Evaluation of Proenkephalin A 119–159 for liberation from renal replacement therapy: an external, multicenter pilot study in critically ill patients with acute kidney injury

Critical Care2023-07-1023 citations

Citrate dose for continuous hemofiltration: effect on calcium and magnesium balance, parathormone and vitamin D status, a randomized controlled trial.

2021-12-115 citations

Effect of Regional Citrate Anticoagulation vs Systemic Heparin Anticoagulation During Continuous Kidney Replacement Therapy on Dialysis Filter Life Span and Mortality Among Critically Ill Patients With Acute Kidney Injury

JAMA2020-10-23330 citations

Regional citrate versus systemic heparin anticoagulation for continuous renal replacement therapy in critically ill patients with acute kidney injury (RICH) trial: study protocol for a multicentre, randomised controlled trial

BMJ Open2019-01-0135 citations