Cisplatin-based induction chemotherapy

DRUG4 trials

Sponsors

Sun Yat-sen University, Ming-Yuan Chen

Conditions

De-escalation TherapyNasopharyngeal CarcinomaNasopharyngeal Carcinoma (NPC)

Phase 3

Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy

RecruitingNCT06092957

Sun Yat-sen UniversityDe-escalation Therapy, Nasopharyngeal Carcinoma

Start: 2023-10-09End: 2031-10-30Target: 504Updated: 2023-12-15

Under Whole-course of Immunotherapy, Gradient Fractionated RT with CCT Versus CFRT with CCT for LANPC Who Achieved PR Post Induction Chemotherapy.

RecruitingNCT06675214

Sun Yat-sen UniversityDe-escalation Therapy, Nasopharyngeal Carcinoma

Start: 2024-07-30End: 2030-07-31Target: 586Updated: 2024-11-05

Reduced-dose Versus Conventional-dose Intensity-modulated Radiation Therapy for Locally Advanced Nasopharyngeal Carcinoma With Remission After Induction Chemotherapy and Immunotherapy

RecruitingNCT07328841

Ming-Yuan ChenNasopharyngeal Carcinoma (NPC)

Start: 2025-11-18End: 2032-06-30Target: 456Updated: 2026-01-09

40.2Gy Versus 49.2Gy Radiotherapy in Low-Risk Target Volume for Chemosensitive Stage II Nasopharyngeal Carcinoma

RecruitingNCT07328854

Ming-Yuan ChenNasopharyngeal Carcinoma

Start: 2025-11-20End: 2032-06-30Target: 346Updated: 2026-01-09