Cisplatin Teva® 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung
Sponsors
Bristol-Myers Squibb International Corporation, Merck Sharp & Dohme LLC, Bristol Myers Squibb International Corporation, Bristol-Myers Squibb Services Unlimited Company, Swiss Group for Clinical Cancer Research
Conditions
Bladder Cancer
Muscle-Invasive Bladder CancerEarly Stage Non-Small Cell Lung Cancer (NSCLC)First-line treatment of participants with metastatic nonsmall cell lung cancerN2)Non-Small Cell Lung CancerPreviously Untreated Advanced or Metastatic Non-Squamous Non−Small Cell Lung CancerPreviously Untreated Locally Advanced Non-small Cell Lung Cancer (LA NSCLC)Resectable
Phase 1
Phase 2
TRAP-BTC
Efficacy and safety of GemCis plus Trastuzumab plus Pembrolizumab in previously untreated HER2-positive biliary tract cancer
RecruitingCTIS2023-505722-33-00
Start: 2024-04-15Target: 24Updated: 2026-01-22
Immune-modulatory radiotherapy to enhance the effects of neoadjuvant PD-L1 blockade after neoadjuvant chemotherapy in patients with resectable stage III(N2) non-small cell lung cancer (NSCLC). A multicenter phase II trial.
Active, not recruitingCTIS2023-504536-18-00
Start: 2024-07-31Target: 10Updated: 2025-10-22
EDEN : Prospective therapeutic de-escalation and miRNA-M371 biomarker evaluation Phase II study for stage IIa/IIb < 3 cm seminomas
RecruitingCTIS2024-514636-25-00
Start: 2023-05-04Target: 90Updated: 2024-11-08
Prospective randomized Phase II trial on Induction Immunochemotherapy followed by surgery or definitive chemoradiation and consolidation Durvalumab (MEDI4736) in resectable and borderline resectable stage IIIA/B NSCLC
RecruitingCTIS2024-516367-80-00
Start: 2025-04-24Target: 176Updated: 2025-10-10
Phase 3
A Phase 3 Randomized, Open-label Clinical Study to Evaluate the Pharmacokinetics and Safety of Subcutaneous Pembrolizumab Coformulated With Hyaluronidase (MK-3475A) Versus Intravenous Pembrolizumab, Administered With Chemotherapy, in the First-line Treatment of Participants With Metastatic Non-small Cell Lung Cancer
Active, not recruitingCTIS2022-501506-36-00
Start: 2023-04-11Target: 100Updated: 2025-08-20
A Phase 3, Randomized, Open Label Study to Compare Nivolumab plus Concurrent Chemoradiotherapy (CCRT) followed by Nivolumab plus Ipilimumab or Nivolumab plus CCRT Followed by Nivolumab vs CCRT followed by Durvalumab in Previously Untreated, Locally Advanced Nonsmall Cell Lung Cancer (LA NSCLC)
CompletedCTIS2022-502886-71-00
Start: 2019-11-20End: 2024-05-31Target: 485Updated: 2024-05-20
Randomized, Open-Label, Phase 3 Trial of Nivolumab plus Ipilimumab or Nivolumab plus Platinum-Doublet Chemotherapy versus Platinum-Doublet
Chemotherapy in Early Stage NSCLC
CompletedCTIS2022-501360-18-00
Start: 2017-03-15End: 2024-12-03Target: 194Updated: 2024-12-03
A Phase 3, Randomized, Double-blind Study of Neoadjuvant Chemotherapy plus Nivolumab versus Neoadjuvant Chemotherapy plus Placebo, followed by Surgical Resection and Adjuvant Treatment with Nivolumab or Placebo for Participants with Resectable Stage II-IIIB Non-small Cell Lung Cancer (CheckMate 77T, CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 77T)
Active, not recruitingCTIS2022-502658-15-00
Start: 2019-09-22Target: 252Updated: 2025-10-08
A Phase 3, Randomized Study of Nivolumab plus Ipilimumab in Combination with Chemotherapy vs Chemotherapy alone as First Line Therapy in Stage IV Non-Small Cell Lung Cancer (NSCLC)
CompletedCTIS2023-508757-75-00
Start: 2017-09-18End: 2024-10-18Target: 456Updated: 2024-10-28
A Phase 3, Open-label, Randomized Study of Nivolumab Combined with Ipilimumab, or with Standard of Care Chemotherapy, versus Standard of Care Chemotherapy in Participants with Previously Untreated Unresectable or Metastatic Urothelial Cancer
Active, not recruitingCTIS2022-501784-40-00
Start: 2017-05-26Target: 701Updated: 2026-01-26
A Phase 3, Randomized, Study of Neoadjuvant Chemotherapy alone versus
Neoadjuvant Chemotherapy plus Nivolumab or Nivolumab and BMS-
986205, Followed by Continued Post- Surgery Therapy with Nivolumab or
Nivolumab and BMS-986205 in Participants with Muscle-Invasive Bladder
Cancer
Active, not recruitingCTIS2024-512158-12-00
Start: 2018-12-14Target: 386Updated: 2025-10-20
A Phase III, Randomised, Open-Label Study of Savolitinib in Combination With Osimertinib Versus Platinum-Based Doublet Chemotherapy in Participants With EGFR Mutated MET-Overexpressed and/or Amplified, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Progressed on Treatment With Osimertinib (SAFFRON)
Active, not recruitingCTIS2024-511169-12-00
Start: 2023-03-28Target: 87Updated: 2025-11-17
A Phase I-III, Multicenter Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Patients with Resectable Stage I-III Non-Small Cell Lung Cancer, selected according to Biomarker Status
RecruitingCTIS2024-511239-91-00
Start: 2025-05-05Target: 54Updated: 2025-11-10
A PHASE III, RANDOMIZED, OPEN-LABEL STUDY EVALUATING THE EFFICACY AND SAFETY OF DIVARASIB AND PEMBROLIZUMAB VERSUS PEMBROLIZUMAB AND PEMETREXED AND CARBOPLATIN OR CISPLATIN IN PATIENTS WITH PREVIOUSLY UNTREATED, KRAS G12C-MUTATED, ADVANCED OR METASTATIC NON-SQUAMOUS NON-SMALL CELL LUNG CANCER
RecruitingCTIS2024-518365-10-00
Start: 2025-10-28Target: 282Updated: 2026-01-13