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Cisplatin NeoCorp 1 mg/ml - Konzentrat zur Herstellung einer Infusionslösung

DRUG16 trials

Sponsors

Bristol-Myers Squibb International Corporation, Bristol Myers Squibb International Corporation, Incyte Corp., AstraZeneca AB, Bristol-Myers Squibb Services Unlimited Company

Conditions

Advanced Hepatobiliary CancerAdvanced Non-Small Cell Lung CancerAnaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer (NSCLC)Bladder Cancer Muscle-Invasive Bladder CancerCompletely resectedEarly Stage Non-Small Cell Lung Cancer (NSCLC)HER2-negative breast cancerHER2-negative breast cancer patients with high relapse risk after standard neoadjuvant treatment

Phase 1

Phase 2

Phase 3

A Phase 3, Randomized, Open Label Study to Compare Nivolumab plus Concurrent Chemoradiotherapy (CCRT) followed by Nivolumab plus Ipilimumab or Nivolumab plus CCRT Followed by Nivolumab vs CCRT followed by Durvalumab in Previously Untreated, Locally Advanced Nonsmall Cell Lung Cancer (LA NSCLC)
CompletedCTIS2022-502886-71-00
Bristol Myers Squibb International CorporationPreviously Untreated Locally Advanced Non-small Cell Lung Cancer (LA NSCLC)
Start: 2019-11-20End: 2024-05-31Target: 485Updated: 2024-05-20
Randomized, Open-Label, Phase 3 Trial of Nivolumab plus Ipilimumab or Nivolumab plus Platinum-Doublet Chemotherapy versus Platinum-Doublet Chemotherapy in Early Stage NSCLC
CompletedCTIS2022-501360-18-00
Bristol-Myers Squibb International CorporationEarly Stage Non-Small Cell Lung Cancer (NSCLC)
Start: 2017-03-15End: 2024-12-03Target: 194Updated: 2024-12-03
A Phase 3, Randomized, Double-blind Study of Neoadjuvant Chemotherapy plus Nivolumab versus Neoadjuvant Chemotherapy plus Placebo, followed by Surgical Resection and Adjuvant Treatment with Nivolumab or Placebo for Participants with Resectable Stage II-IIIB Non-small Cell Lung Cancer (CheckMate 77T, CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 77T)
Active, not recruitingCTIS2022-502658-15-00
Bristol-Myers Squibb Services Unlimited CompanyResectable Stage II-IIIB Non-small cell lung cancer
Start: 2019-09-22Target: 252Updated: 2025-10-08
A Phase 3, Randomized Study of Nivolumab plus Ipilimumab in Combination with Chemotherapy vs Chemotherapy alone as First Line Therapy in Stage IV Non-Small Cell Lung Cancer (NSCLC)
CompletedCTIS2023-508757-75-00
Bristol Myers Squibb International CorporationStage IV Non-Small Cell Lung Cancer (NSCLC)
Start: 2017-09-18End: 2024-10-18Target: 456Updated: 2024-10-28
A Phase 3, Open-label, Randomized Study of Nivolumab Combined with Ipilimumab, or with Standard of Care Chemotherapy, versus Standard of Care Chemotherapy in Participants with Previously Untreated Unresectable or Metastatic Urothelial Cancer
Active, not recruitingCTIS2022-501784-40-00
Bristol Myers Squibb International CorporationUntreated Unresectable or Metastatic Urothelial Cancer
Start: 2017-05-26Target: 701Updated: 2026-01-26
A Phase III, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients with Completely Resected Stage Ib (Tumors ≥ 4 Cm) to Stage IIIa Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer
Active, not recruitingCTIS2023-506861-76-00
F. Hoffmann-La Roche AGAnaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer (NSCLC), Completely resected, Stage Ib (tumors ≥ 4 cm) to Stage IIIa
Start: 2018-08-09Target: 55Updated: 2025-05-26
A Phase 3, Randomized, Study of Neoadjuvant Chemotherapy alone versus Neoadjuvant Chemotherapy plus Nivolumab or Nivolumab and BMS- 986205, Followed by Continued Post- Surgery Therapy with Nivolumab or Nivolumab and BMS-986205 in Participants with Muscle-Invasive Bladder Cancer
Active, not recruitingCTIS2024-512158-12-00
Bristol-Myers Squibb Services Unlimited CompanyBladder Cancer Muscle-Invasive Bladder Cancer
Start: 2018-12-14Target: 386Updated: 2025-10-20
A Randomized, Double Blind, Phase 3 Study of Platinum-Based Chemotherapy With or Without INCMGA00012 in First-Line Metastatic Squamous and Nonsquamous Non–Small Cell Lung Cancer (POD1UM-304)
Active, not recruitingCTIS2022-501987-16-00
Incyte Corp.Metastatic nonsquamous or squamous non-small cell lung cancer
Start: 2020-10-02Target: 14Updated: 2025-08-05
Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant treatment - SASCIA
Active, not recruitingCTIS2023-510390-33-00
GBG Forschungs GmbHHER2-negative breast cancer, HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant treatment
Start: 2020-10-23Target: 1386Updated: 2025-12-18
A Phase I-III, Multicenter Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Patients with Resectable Stage I-III Non-Small Cell Lung Cancer, selected according to Biomarker Status
RecruitingCTIS2024-511239-91-00
F. Hoffmann-La Roche AGResectable Stage I-III Non-Small Cell Lung Cancer (NSCLC)
Start: 2025-05-05Target: 54Updated: 2025-11-10
A PHASE III, RANDOMIZED, OPEN-LABEL STUDY EVALUATING THE EFFICACY AND SAFETY OF DIVARASIB AND PEMBROLIZUMAB VERSUS PEMBROLIZUMAB AND PEMETREXED AND CARBOPLATIN OR CISPLATIN IN PATIENTS WITH PREVIOUSLY UNTREATED, KRAS G12C-MUTATED, ADVANCED OR METASTATIC NON-SQUAMOUS NON-SMALL CELL LUNG CANCER
RecruitingCTIS2024-518365-10-00
F. Hoffmann-La Roche AGPreviously Untreated Advanced or Metastatic Non-Squamous Non−Small Cell Lung Cancer
Start: 2025-10-28Target: 282Updated: 2026-01-13