Cisplatin (or alternative)

DRUG2 trials

Sponsors

UNC Lineberger Comprehensive Cancer Center

Conditions

Carcinoma, Squamous CellHead and Neck NeoplasmsOropharyngeal Neoplasms

Phase 2

De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

CompletedNCT02281955

UNC Lineberger Comprehensive Cancer CenterCarcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

Start: 2014-08-31End: 2024-11-24Updated: 2025-01-07

P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC

CompletedNCT03077243

UNC Lineberger Comprehensive Cancer CenterCarcinoma, Squamous Cell, Head and Neck Neoplasms, Oropharyngeal Neoplasms

Start: 2016-12-31End: 2022-12-14Updated: 2024-05-02

Related Papers

[Update on HPV-associated head and neck cancer-highlights from the 2019 ASCO Annual Meeting].

2019-12-014 citations

Mature results of the LCCC1413 phase II trial of de-intensified chemoradiotherapy for HPV-associated oropharyngeal squamous cell carcinoma.

Journal of Clinical Oncology2019-05-205 citations

PIK3CA mutation as a prognostic factor in HPV-associated oropharynx cancer.

Journal of Clinical Oncology2019-05-201 citations

Multiplexed digital PCR for detection of HPV in tissue samples from oropharyngeal cancer patients.

Journal of Clinical Oncology2019-05-201 citations