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Circulating Tumor DNA test (ctDNA test)

DIAGNOSTIC_TEST2 trials

Sponsors

University of Maryland, Baltimore

Conditions

HPV (Human Papillomavirus)-Associated CarcinomaHPV 16 Positive Oropharyngeal Tumors (OPC)HPV Positive Oropharyngeal Squamous Cell CarcinomaHead and Neck CancerHead and Neck Squamous Cell CancerHead and Neck Squamous Cell CarcinomaOropharyngeal CancerOropharyngeal Carcinoma

Phase 2

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)
RecruitingNCT06088381
University of Maryland, BaltimoreHead and Neck Cancer, Head and Neck Squamous Cell Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma +2
Start: 2024-03-07End: 2030-12-18Target: 61Updated: 2025-11-07
A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)
Not yet recruitingNCT07418034
University of Maryland, BaltimoreHead and Neck Cancer, Head and Neck Squamous Cell Cancer, Head and Neck Squamous Cell Carcinoma +11
Start: 2026-09-01End: 2033-05-01Target: 132Updated: 2026-08-14