CIN-107

Study to Evaluate the Pharmacokinetics of CIN-107 in Subjects With Varying Degrees of Renal Function

Study With CIN-107 Following Multiple Oral Ascending Doses in Healthy Subjects

Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy Subjects

A Study of CIN-107 in Adults With Treatment-Resistant Hypertension (rHTN)

A Study of CIN-107 in Patients With Uncontrolled Hypertension

A Study to Evaluate CIN-107 for the Treatment of Patients With Uncontrolled Hypertension and Chronic Kidney Disease

Open-Label Extension Study of Patients Previously Enrolled in Study CIN-107-124