Cimzia

DRUG8 trials

Conditions

Crohn DiseaseCrohn's DiseaseRheumatoid ArthritisUlcerative Colitis

Phase 2

Study of Cimzia for the Treatment of Ulcerative Colitis

CompletedNCT01090154

University of WashingtonUlcerative Colitis

Start: 2010-12-01End: 2021-12-10Updated: 2021-12-14

Phase 3

A Study to Evaluate Safety of Long Term Therapy of Certolizumab Pegol Patients With Crohn's Disease

CompletedNCT00552344

UCB BIOSCIENCES GmbHCrohn Disease

Start: 2008-05-31End: 2014-12-31Updated: 2018-08-09

Phase 4

Can TNF-Alpha Incomplete Secondary Responders Attain a Safe and Efficacious Response Switching to Cimzia

CompletedNCT01147341

Michael Schiff, MDRheumatoid Arthritis

Start: 2010-07-31End: 2012-01-31Updated: 2014-06-09

Active Conventional Therapy Compared to Three Different Biologic Treatments in Early Rheumatoid Arthritis With Subsequent Dose Reduction

NCT01491815

Karolinska InstitutetRheumatoid Arthritis

Start: 2012-12-14End: 2023-12-31Updated: 2022-07-08

Cimzia Versus Mesalamine for Crohn's Recurrence

TerminatedNCT01696942

Milton S. Hershey Medical CenterCrohn's Disease

Start: 2013-02-28End: 2016-06-30Updated: 2018-01-12

Dose Reduction for Early Rheumatoid Arthritis Patients With Low Disease Activity

NCT02466581

Karolinska InstitutetRheumatoid Arthritis

Start: 2015-02-03End: 2023-12-31Updated: 2022-07-08

Unknown Phase

SECURE, the Cimzia ® Crohn's Disease Post-Marketing Registry

CompletedNCT00844285

UCB BIOSCIENCES, Inc.Crohn's Disease

Start: 2009-01-30End: 2020-08-21Updated: 2023-05-06

Novel Imaging Markers for Rheumatoid Arthritis

CompletedNCT01773681

University of California, San FranciscoRheumatoid Arthritis

Start: 2013-10-31End: 2018-03-31Updated: 2018-11-30

2026-04-01

Glucocorticoid treatment in early rheumatoid arthritis is independently associated with increased PCSK9 levels: data from a randomised controlled trial

RMD Open2025-06-01

OP0327 TAPERING AND DISCONTINUATION OF GLUCOCORTICOIDS IN EARLY RHEUMATOID ARTHRITIS: THE RISK OF FLARE

Annals of the Rheumatic Diseases2025-06-01

Certolizumab Pegol Treatment in Patients With Crohn’s Disease: Final Safety Data From the SECURE Registry

Crohn s & Colitis 3602024-12-301 citations

Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis: data from a randomised controlled trial.

2024-11-145 citations

Obesity is a risk factor for poor response to treatment in early rheumatoid arthritis: a NORD-STAR study

RMD Open2024-04-0118 citations

Urinary prostanoids are elevated by anti-TNF and anti-IL6 receptor disease-modifying antirheumatic drugs but are not predictive of response to treatment in early rheumatoid arthritis.

2024-03-051 citations

Certolizumab pegol, abatacept, tocilizumab or active conventional treatment in early rheumatoid arthritis: 48-week clinical and radiographic results of the investigator-initiated randomised controlled NORD-STAR trial.

2023-07-0929 citations

Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis-a spin-off study of the NORD-STAR randomized clinical trial.

2021-07-1311 citations

Active conventional treatment and three different biological treatments in early rheumatoid arthritis: phase IV investigator initiated, randomised, observer blinded clinical trial

BMJ2020-12-02108 citations

Head-to-head comparison of aggressive conventional therapy and three biological treatments and comparison of two de-escalation strategies in patients who respond to treatment: study protocol for a multicenter, randomized, open-label, blinded-assessor, phase 4 study.

2017-04-0426 citations

Safety of Long-term Treatment With Certolizumab Pegol in Patients With Crohn's Disease, Based on a Pooled Analysis of Data From Clinical Trials.

2016-07-2517 citations

Long-Term Safety and Efficacy of Certolizumab Pegol Therapy in Patients With Moderate to Severe Crohnʼs Disease: 5-Year Results

The American Journal of Gastroenterology2015-10-011 citations