Choline bitartrate

DRUG11 trials

Sponsors

University of Minnesota, Columbia University, The Cleveland Clinic, Vital Pakistan Trust, Wayne State University

Conditions

Alcohol Related Neurodevelopmental DisorderAnemiaArsenic Metabolites Measured in UrineBrain DevelopmentCardiovascular Risk FactorCholine NutritionFetal Alcohol Spectrum DisordersFetal Alcohol Syndrome

Phase 1

Postnatal Choline Supplementation in Children With Prenatal Alcohol Exposure

CompletedNCT01149538

University of MinnesotaAlcohol Related Neurodevelopmental Disorder, Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome +2

Start: 2010-07-31End: 2014-09-30Updated: 2016-12-19

Phase 2

Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders

CompletedNCT02735473

University of MinnesotaFetal Alcohol Spectrum Disorders

Start: 2016-06-30End: 2021-09-10Updated: 2022-11-01

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

RecruitingNCT04395196

Wayne State UniversityFetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome

Start: 2023-04-13End: 2028-05-15Target: 288Updated: 2026-07-09

Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders Study

Active, not recruitingNCT05108974

Jeff WozniakFetal Alcohol Spectrum Disorders

Start: 2021-10-22End: 2027-07-31Updated: 2026-07-08

Choline and Iron Deficiency

RecruitingNCT06527391

University of MinnesotaAnemia, Pediatric Iron Deficiency

Start: 2025-08-11End: 2027-09-21Target: 300Updated: 2025-08-27

Pilot Study of Prenatal Choline Supplementation

RecruitingNCT07699393

Wayne State UniversityBrain Development, Choline Nutrition

Start: 2026-07-08End: 2028-05-15Target: 50Updated: 2026-07-14

Phase 4

A Preliminary Study of Choline and Betaine Supplementation Among Adults Exposed to Arsenic in Bangladesh

CompletedNCT01749982

Columbia UniversityArsenic Metabolites Measured in Urine

Start: 2012-12-31End: 2014-08-31Updated: 2014-08-28

Effects of a Nutraceutic Compound on Cognitive Impairment

CompletedNCT06200883

Federico II UniversityMild Cognitive Impairment

Start: 2022-09-01End: 2023-11-01Updated: 2024-01-11

Unknown Phase

Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans

CompletedNCT03039023

The Cleveland ClinicCardiovascular Risk Factor

Start: 2016-09-02End: 2020-09-03Updated: 2026-07-13

Nutritional Support and Prophylaxis Doses of Azithromycin for Pregnant Women - Mumta Pregnant Women Trial

Vital Pakistan TrustUndernutrition

Start: 2019-07-22End: 2023-12-31Updated: 2022-10-13

Exploratory Trial of Choline Supplementation for Fetal Alcohol Syndrome

Active, not recruitingPACTR202005864845358

NIH National Institute on Alcohol Abuse and AlcoholismMental and Behavioural Disorders Nervous System Diseases Nutritional, Metabolic, Endocrine Pregnancy and Childbirth Paediatrics

Start: 2012-04-01Target: 70Updated: 2026-06-22

Related Papers

Supplemental choline to prevent and treat learning and memory deficits of early-life iron deficiency (The SupCHO Study): study protocol for a randomized, placebo-controlled trial in Ugandan infants with iron deficiency anemia.

2025-11-19

Choline enhances elicited imitation memory performance in preschool children with prenatal alcohol exposure: a cumulative report of 3 randomized controlled trials.

2025-02-141 citations

Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes

Journal of Neurodevelopmental Disorders2022-12-0127 citations

Polymorphisms in SLC44A1 are associated with cognitive improvement in children diagnosed with fetal alcohol spectrum disorder: an exploratory study of oral choline supplementation

UNC Libraries2022-04-20

Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder

UNC Libraries2022-02-19

Nutritional support and prophylaxis of azithromycin for pregnant women to improve birth outcomes in peri-urban slums of Karachi, Pakistan-a protocol of multi-arm assessor-blinded randomized controlled trial (Mumta PW trial).

2022-01-037 citations

Polymorphisms in SLC44A1 are associated with cognitive improvement in children diagnosed with fetal alcohol spectrum disorder: an exploratory study of oral choline supplementation.

2021-08-0116 citations

Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder.

2020-03-1283 citations

Choline supplementation in children with fetal alcohol spectrum disorders: a randomized, double-blind, placebo-controlled trial.

2015-10-0785 citations