chlorproguanil-dapsone

DRUG5 trials

Sponsors

Centers for Disease Control and Prevention, London School of Hygiene and Tropical Medicine, GlaxoSmithKline

Conditions

AnemiaMalariaMalaria, Falciparum

Phase 1

Chlorproguanil-Dapsone in Pregnant Women

TerminatedNCT00126971

Centers for Disease Control and PreventionMalaria

Start: 2005-07-31Updated: 2025-04-20

Phase 2

Kilimanjaro IPTi Drug Options Trial

CompletedNCT00158574

London School of Hygiene and Tropical MedicineMalaria

Start: 2005-01-31End: 2008-06-30Updated: 2017-01-12

Phase 3

A Trial of Antimalarial Drugs Used in Pregnancy in Tanzania

CompletedNCT00146731

London School of Hygiene and Tropical MedicineMalaria

Start: 2004-01-31End: 2007-09-30Updated: 2017-01-12

Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria

CompletedNCT00371735

GlaxoSmithKlineMalaria, Falciparum

Start: 2006-04-30End: 2007-05-31Updated: 2016-12-05

Unknown Phase

Intermittent Preventive Treatment With Antimalarials in Kenyan Infants

CompletedNCT00111163

Centers for Disease Control and PreventionAnemia, Malaria

Start: 2004-03-31End: 2008-03-31Target: 1516Updated: 2012-09-27

Related Papers

Clinical spectrum and severity of hemolytic anemia in glucose 6-phosphate dehydrogenase-deficient children receiving dapsone.

2012-09-1985 citations

Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials.

2011-08-1764 citations

Duration of protection against clinical malaria provided by three regimens of intermittent preventive treatment in Tanzanian infants.

2010-03-0123 citations

Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial.

2009-09-1683 citations

Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.

2009-04-0845 citations

High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581.

2009-02-24132 citations