Chloroquine prophylaxis

DRUG4 trials

Sponsors

Ministry of Health and Medical Services, Solomon Islands, Radboud University Medical Center

Conditions

MalariaMalaria in PregnancyPlasmodium FalciparumPlasmodium Falciparum Malaria

Phase 4

A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands

TerminatedNCT00964691

Ministry of Health and Medical Services, Solomon IslandsMalaria, Malaria in Pregnancy

Start: 2009-08-31End: 2010-08-31Target: 2504Updated: 2010-07-07

Unknown Phase

Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis

CompletedNCT01218893

Radboud University Medical CenterPlasmodium Falciparum Malaria

Start: 2011-04-30End: 2012-03-31Updated: 2012-04-02

Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis

CompletedNCT01236612

Radboud University Medical CenterPlasmodium Falciparum Malaria

Start: 2011-04-30End: 2012-06-30Updated: 2014-01-22

Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis

CompletedNCT01422954

Radboud University Medical CenterMalaria, Plasmodium Falciparum

Start: 2012-01-31End: 2013-04-30Updated: 2013-04-29

Related Papers

Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites

PLoS ONE2015-05-0153 citations

Sporozoite Immunization of Human Volunteers under Mefloquine Prophylaxis Is Safe, Immunogenic and Protective: A Double-Blind Randomized Controlled Clinical Trial

PLoS ONE2014-11-1450 citations

Memory B-Cell and Antibody Responses Induced by Plasmodium falciparum Sporozoite Immunization

The Journal of Infectious Diseases2014-06-2555 citations

Cytotoxic Markers Associate With Protection Against Malaria in Human Volunteers Immunized With<i>Plasmodium falciparum</i>Sporozoites

The Journal of Infectious Diseases2014-05-27102 citations

Intermittent preventive treatment with sulfadoxine-pyrimethamine versus weekly chloroquine prophylaxis for malaria in pregnancy in Honiara, Solomon Islands: a randomised trial

PubMed2013-06-294 citations