Chloroquine phosphate

DRUG11 trials

Conditions

Atrial FibrillationCOVID-19Covid-19HIV InfectionsIdiopathic Inflammatory Myopathy (including dermatomyositis or polymyositis)MalariaPancreatic Adenocarcinoma MetastaticPancreatic Cancer Metastatic

Phase 1

Dose Escalation PfSPZ-CVac

CompletedNCT03083847

National Institute of Allergy and Infectious Diseases (NIAID)Malaria

Start: 2017-06-05End: 2019-06-26Updated: 2021-06-01

Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...

CompletedNCT03952650

National Institute of Allergy and Infectious Diseases (NIAID)Malaria

Start: 2019-05-23End: 2021-02-10Updated: 2022-07-12

Chloroquine Phosphate Prophylactic Use in Health Personnel Exposed to COVID-19 Patients

NCT04443270

CMN 20 de NoviembreCOVID-19

Start: 2020-07-27End: 2021-01-31Target: 200Updated: 2020-07-14

The Seven Trial: Exploiting the Unfolded Protein Response

Active, not recruitingNCT06076837

HonorHealth Research InstitutePancreatic Adenocarcinoma Metastatic, Pancreatic Cancer Metastatic

Start: 2025-01-09End: 2026-12-31Updated: 2026-01-12

Phase 2

Investigating the Anti-Human Immunodeficiency Virus (HIV) & Anti-inflammatory Effect of Chloroquine

TerminatedNCT00308620

University of MinnesotaHIV Infections

Start: 2006-03-31End: 2009-06-30Updated: 2020-06-04

Chloroquine for Patients With Symptomatic Persistent Atrial Fibrillation: A Prospective Pilot Study

RecruitingNCT02932007

University of South FloridaAtrial Fibrillation

Start: 2017-03-28End: 2020-09-30Target: 40Updated: 2019-08-19

The Vietnam Chloroquine Treatment on COVID-19

CompletedNCT04328493

Oxford University Clinical Research Unit, VietnamCOVID-19, SARS-CoV-2 Infection

Start: 2020-04-07End: 2020-09-10Updated: 2021-05-24

Phase 3

Lagos COVID-19 Chloroquine Treatment Trial (LACCTT)

Active, not recruitingPACTR202004801273802

LAGOS STATE GOVERNMENTCovid-19

Start: 2020-04-20Target: 800Updated: 2026-01-27

C0251010 - A PHASE 3, MULTI-CENTER, OPEN-LABEL EXTENSION STUDY TO INVESTIGATE THE LONG-TERM SAFETY, TOLERABILITY, AND EFFICACY OF DAZUKIBART IN PARTICIPANTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH DERMATOMYOSITIS OR POLYMYOSITIS)

RecruitingCTIS2024-514648-10-00

Pfizer Inc.Idiopathic Inflammatory Myopathy (including dermatomyositis or polymyositis)

Start: 2025-03-14Target: 21Updated: 2025-11-25

Phase 4

Effectiveness of Malaria Treatment in Mexico

CompletedNCT02394197

LILIA GONZALEZ CERONMalaria

Start: 2008-02-29End: 2010-09-30Updated: 2015-03-20

Chloroquine as Antiviral Treatment in Coronavirus Infection 2020

CompletedNCT04331600

Wroclaw Medical UniversityCOVID-19

Start: 2020-04-16End: 2020-12-17Updated: 2021-02-11

Journal of Clinical Oncology2025-05-28

A multi-centre, randomized, double-blind, placebo-controlled clinical trial of the efficacy and safety of chloroquine phosphate, hydroxychloroquine sulphate and lopinavir/ritonavir for the treatment of COVID-19 in Lagos State: study protocol for a randomized controlled trial

Trials2021-12-013 citations

Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity.

2021-06-3091 citations

A multi centre randomized open label trial of chloroquine for the treatment of adults with SARS-CoV-2 infection in Vietnam.

2020-06-121 citations

Effectiveness of combined chloroquine and primaquine treatment in 14 days versus intermittent single dose regimen, in an open, non-randomized, clinical trial, to eliminate Plasmodium vivax in southern Mexico

Malaria Journal2015-10-3025 citations